A class of small 1-methylquinolinium-based molecular fluorescent probes with high
specificity in DNA G-quadruplex structures imaging in live cells was developed through the …

G-quadruplex DNAs are secondary DNA structures formed in guanine-rich genome
sequences, such as telomeres. Due to the increased metabolic activities of cancer cells, the …

Triphenylmethane (TPM) dyes normally render rather weak fluorescence due to easy
vibrational deexcitation. However, when they stack onto the two external G-quartets of a G …

A library of 52 distyryl and 9 mono-styryl cationic dyes was synthesized and investigated
with respect to their optical properties, propensity to aggregation in aqueous medium, and …

G-quadruplex (G4) forming sequences commonly exist in the genome and are closely
related to gene regulation and expression. Development of a fluorescent probe that can …

Fluorimetric titrations were performed to gain insight into parameters that govern the
association of thiazole orange (TO) and G-quadruplex-DNA (G4-DNA). Use of loop …

New monomethine, unsymmetrical styryl dyes consisting of benzothiazole and N-
methylpiperazine or N-phenylpiperazine scaffolds were synthesized, and their binding …

Searching for specific G-quadruplex DNA probes is important for study of the function of G-
rich gene sequence, as well as design of novel effective anticancer drugs. In this paper, a …

G-quadruplexes are guanine-rich nucleic acid sequences that can act as universal signal-
transducers and generate colorimetric, fluorescence, and chemiluminescence signals when …

Human telomeres play a key role in protecting chromosomal ends from fusion events; they
are composed of d (TTAGGG) repeats, ranging in size from 3 to 15 kb. They form G …