Spectroscopic analysis reveals the effect of a single nucleotide bulge on G-quadruplex structures
Here we investigate and reveal the effect of bulge position and bulge identity on G-
quadruplexes using label-free spectroscopic techniques. Notably, we report significant …
quadruplexes using label-free spectroscopic techniques. Notably, we report significant …
Specific Binding of Anionic Porphyrin and Phthalocyanine to the G-Quadruplex with a Variety of in Vitro and in Vivo Applications
H Yaku, T Murashima, D Miyoshi, N Sugimoto - Molecules, 2012 - mdpi.com
The G-quadruplex, a four-stranded DNA structure with stacked guanine tetrads (G-quartets),
has recently been attracting attention because of its critical roles in vitro and in vivo. In …
has recently been attracting attention because of its critical roles in vitro and in vivo. In …
Screening of DNA G-quadruplex stabilizing ligands by nano differential scanning fluorimetry
B Pagano, N Iaccarino, A Di Porzio, A Randazzo… - Analyst, 2019 - pubs.rsc.org
G-quadruplex (G4) nucleic acid structures are involved in a number of different diseases and
their drug-induced stabilization is deemed to be a promising therapeutic approach. Herein is …
their drug-induced stabilization is deemed to be a promising therapeutic approach. Herein is …
Revealing the specific interactions between G-quadruplexes and ligands by surface-enhanced Raman spectroscopy
Y Bao, X Zhang, X Xiang, Y Zhang, X Guo - International Journal of …, 2022 - Elsevier
Abstract G-quadruplexes (G4s) regulate a variety of physiological functions related to
diseases and life elongation. Therefore, G4 binding ligands, such as potential drugs in gene …
diseases and life elongation. Therefore, G4 binding ligands, such as potential drugs in gene …
Colorimetric and fluorescence detection of G-quadruplex nucleic acids with a coumarin–benzothiazole probe
J Yan, Y Tian, J Tan, Z Huang - Analyst, 2015 - pubs.rsc.org
A colorimetric and red-emitting fluorescent dual probe for G-quadruplexes was devised with
a conjugated coumarin–benzothiazole scaffold. Its significant and distinct changes in both …
a conjugated coumarin–benzothiazole scaffold. Its significant and distinct changes in both …
Functional evaluation of novel chromon derivative compounds for recognition of G-quadruplex structure
Currently, G-quadruplex structure targeting strategies are considered as a promising
anticancer approach. The purpose of this research is to expand the options for G-quadruplex …
anticancer approach. The purpose of this research is to expand the options for G-quadruplex …
Correlations between fluorescence emission and base stacks of nucleic acid G-quadruplexes
S Gao, Y Cao, Y Yan, X Xiang, X Guo - RSC advances, 2016 - pubs.rsc.org
The aromatic 5/6 ring overlaps at the interface of 5′-5′ stacked dimers formed by two
parallel G-quadruplexes have been demonstrated to produce a characteristic 385 nm …
parallel G-quadruplexes have been demonstrated to produce a characteristic 385 nm …
Verification of intramolecular hybrid/parallel G-quadruplex structure under physiological conditions using novel cyanine dye H-aggregates: Both in solution and on Au …
Q Yang, JF Xiang, S Yang, Q Li, Q Zhou… - Analytical …, 2010 - ACS Publications
The H-aggregates of a novel cyanine dye, 3, 3′-di (3-sulfopropyl)-4, 5, 4′, 5′-dibenzo-9-
methyl-thiacarbocyanine triethylammonium salt (MTC), have been fabricated to verify …
methyl-thiacarbocyanine triethylammonium salt (MTC), have been fabricated to verify …
Circular dichroism of DNA G-quadruplexes: combining modeling and spectroscopy to unravel complex structures
We report on the comparison between the computational and experimental determination of
electronic circular dichroism spectra of different guanine quadruplexes obtained from human …
electronic circular dichroism spectra of different guanine quadruplexes obtained from human …
Human telomeric G-quadruplex DNA interactions of N-phenanthroline glycosylamine copper (II) complexes
K Duskova, S Sierra, MS Arias-Pérez, L Gude - Bioorganic & Medicinal …, 2016 - Elsevier
We report in this article the interactions of five N-(1, 10-phenanthrolin-5-yl)-β-
glycopyranosylamine copper (II) complexes with G-quadruplex DNA. Specifically, the …
glycopyranosylamine copper (II) complexes with G-quadruplex DNA. Specifically, the …