Probing metal-dependent G-quadruplexes using the intrinsic fluorescence of DNA

A Lopez, J Liu - Chemical Communications, 2022 - pubs.rsc.org
Probing metal-dependent G-quadruplexes using the intrinsic fluorescence of DNA - Chemical
Communications (RSC Publishing) DOI:10.1039/D2CC03967B Royal Society of Chemistry View …

[HTML][HTML] G-quadruplex and calf thymus DNA interaction of quaternized tetra and octa pyridyloxy substituted indium (III) phthalocyanines

E Bağda, E Bağda, M Durmuş - Journal of Photochemistry and …, 2017 - Elsevier
The interactions of small molecules with G-quadruplex and double stranded DNA are
important due to their potential biological and medical usages. In the present paper, the …

Multicharged phthalocyanines as selective ligands for G-quadruplex DNA structures

CIV Ramos, SP Almeida, LMO Lourenço, PMR Pereira… - Molecules, 2019 - mdpi.com
The stabilization of G-Quadruplex DNA structures by ligands is a promising strategy for
telomerase inhibition in cancer therapy since this enzyme is responsible for the unlimited …

G-quadruplexes as sensing probes

B Ruttkay-Nedecky, J Kudr, L Nejdl, D Maskova… - Molecules, 2013 - mdpi.com
Guanine-rich sequences of DNA are able to create tetrastranded structures known as G-
quadruplexes; they are formed by the stacking of planar G-quartets composed of four …

Carbazole-based fluorescent probes for G-quadruplex DNA targeting with superior selectivity and low cytotoxicity

QQ Yu, MQ Wang - Bioorganic & Medicinal Chemistry, 2020 - Elsevier
G-quadruplex DNA plays a very important role in clinical diagnosis and fluorescence
analysis has attracted extensive attention. A class of carbazole-based fluorescent probes for …

Ligand design to acquire specificity to intended G‐quadruplex structures

S Asamitsu, T Bando… - Chemistry–A European …, 2019 - Wiley Online Library
AG‐quadruplex is a nucleic acid secondary structure that is adopted by guanine‐rich
sequences, and is considered to be relevant in various pharmacological and biological …

Recognizing hybrid/mixed G‐quadruplex in human telomeres by using a cyanine dye supramolecule with confocal laser scanning microscopy

Q Yang, J Xiang, S Yang, Q Zhou, Q Li… - Chinese Journal of …, 2010 - Wiley Online Library
Single‐stranded telomeric DNA tends to form a four‐base‐paired planar structure termed G‐
quadruplex. Although kinds of G‐quadruplex structures in vitro have been documented in …

Inhibition of G-quadruplex assembling by DNA ligation: a versatile and non-covalent labeling strategy for bioanalysis

J Ren, J Wang, J Wang, E Wang - Biosensors and Bioelectronics, 2014 - Elsevier
Through tuning relative thermodynamic stabilities (I, II and III), DNA ligation was coupled to
split G-quadruplex probes and a versatile, non-covalent labelling and fluorescent strategy …

Targeting of parallel c-myc G-quadruplex by dimeric cyanine dye supramolecular assembly: dependence on the linker length

L Yu, Q Yang, J Xiang, H Sun, L Wang, Q Li, A Guan… - Analyst, 2015 - pubs.rsc.org
A series of dimeric cyanine dyes were designed to study their recognition for parallel c-myc
G-quadruplex as well as their spectral features in solution. Dimeric cyanine dyes having …

Second generation G-quadruplex stabilizing trimethine cyanines

EA Owens, HT Huynh, EM Stroeva… - Bioconjugate …, 2019 - ACS Publications
G-Quadruplex DNA has been recognized as a highly appealing target for the development
of new selective chemotherapeutics, which could result in markedly reduced toxicity toward …