[HTML][HTML] Experimental models of renal calcium stones in rodents

H Bilbault, JP Haymann - World journal of nephrology, 2016 - ncbi.nlm.nih.gov
In human nephrolithiasis, most stones are containing calcium and are located within urinary
cavities; they may contain monohydrate calcium oxalate, dihydrate calcium oxalate and/or …

Animal model of calcium oxalate nephrolithiasis

SR Khan - Calcium oxalate in biological systems, 2020 - taylorfrancis.com
Crystallization of salts in the urine is a process common to many mammals including
humans. The crystals are either harmlessly excreted as crystalluria particles or are retained …

Animal models of calcium oxalate kidney stone formation

SR Khan - Animal models for the study of human disease, 2013 - Elsevier
Most kidney stones consist of crystals of calcium oxalate (CaOx) and/or calcium phosphate
(CaP), and develop on nidi present on renal papillary surfaces. Stone formation is the last …

Nephrocalcinosis in animal models with and without stones

SR Khan - Urological research, 2010 - Springer
Nephrocalcinosis is the deposition of calcium salts in renal parenchyma and can be
intratubular or interstitial. Animal model studies indicate that intratubular nephrocalcinosis is …

Nephrolithiasis and nephrocalcinosis in rats with small bowel resection

RC O'Connor, EM Worcester, AP Evan, S Meehan… - Urological …, 2005 - Springer
Intestinal resection (IR) may lead to hyperoxaluria and nephrolithiasis. A rat model of IR was
developed, in which kidney stones form. We describe the urine chemistries and …

Experimental induction of calcium oxalate nephrolithiasis in mice

SR Khan, PA Glenton - The Journal of urology, 2010 - auajournals.org
Purpose: The availability of various transgenic and knockout mice provides an excellent
opportunity to better understand the pathophysiology of calcium oxalate stone disease …

Etiology of calcium oxalate nephrolithiasis in rats. I. Can this be a model for human stone formation?

WC De Bruijn, ER Boeve, P Van Run… - Scanning …, 1995 - digitalcommons.usu.edu
Crystal retention is studied in a rat-model system as a possible mechanism for the etiology of
human nephrolithiasis. A crystal-inducing diet (CID) of ethylene glycol plus NH 4 Cl in their …

Nephrocalcinosis: new insights into mechanisms and consequences

BA Vervaet, A Verhulst, PC d'Haese… - Nephrology Dialysis …, 2009 - academic.oup.com
The most common form of renal stone disease, calcium nephrolithiasis, is defined as the
presentation of a macroscopic concrement of inorganic (calcium phosphate and/or calcium …

Urothelium proliferation is a trigger for renal crystal deposits in a murine lithogenesis model

H Bilbault, J Perez, L Huguet, S Vandermeersch… - Scientific Reports, 2018 - nature.com
Most mouse kidney stone models induce nephrocalcinosis rather than urolithiasis. The aim
of our study was to find an accelerated experimental model in order to study the early events …

Understanding the pathophysiology of nephrocalcinosis

G Priante, M Ceol, L Terrin, L Gianesello… - … and Advances in …, 2017 - books.google.com
Many in vitro and in vivo studies on the mechanisms underlying calcium nephrolithiasis
have provided evidence of a frequently associated condition, ie, a microscopic renal crystal …