Background Psychostimulants remain first-line treatment options for the management of
attention-deficit/hyperactivity disorder (ADHD). A multilayer extended-release bead …

Objectives: To assess the efficacy and safety of a methylphenidate hydrochloride extended-
release capsule (MPH-MLR) formulation in treating attention-deficit/hyperactivity disorder …

Objective: The purpose of this study was to assess the time of onset and time course of
efficacy over 12.0 hours of extended-release multilayer bead formulation of methylphenidate …

Abstract Objective: This 5-week, multicenter, double-blind, placebo-controlled, parallel-
group investigation is the first fixed-dose study to evaluate efficacy and tolerability of three …

Objective This was a single-dose, one-period, multicenter, pharmacokinetic (PK) study to
evaluate the PK of methylphenidate (MPH) hydrochloride multilayer extended-release …

OBJECTIVE:: The efficacy and safety of dexmethylphenidate extended release (d-MPH-ER)
was compared to placebo in pediatric patients with attention-deficit/hyperactivity disorder …

Objectives: To study the safety and efficacy of the long-acting methylphenidate formulation
PRC-063 in adolescents with attention-deficit/hyperactivity disorder (ADHD). Methods …

Objective: To examine the efficacy, safety, and tolerability of methylphenidate extended-
release orally disintegrating tablets (MPH XR-ODT) for the treatment of attention …

Objective: This phase 3, laboratory classroom study assessed the efficacy and safety of
methylphenidate hydrochloride extended-release chewable tablets (MPH ERCT) compared …

Objective: To determine the safety and efficacy of PRC-063, a once-daily, multilayer,
extended-release (ER) formulation of methylphenidate (MPH) hydrochloride, in the …