Amorphous solid dispersions (ASDs) have emerged as widespread formulations for drug
delivery of poorly soluble active pharmaceutical ingredients (APIs). Predicting the API …

Amorphous solid dispersions enhance solubility and oral bioavailability of poorly water-
soluble drugs. The escalating number of drugs with poor aqueous solubility, poor …

Amorphous solid dispersions (ASDs) are commonly used to orally deliver small-molecule
drugs that are poorly water-soluble. ASDs consist of drug molecules in the amorphous form …

Amorphous solid dispersion (ASD) formulation development is frequently difficult owing to
the inherent physical instability of the amorphous form, and limited understanding of the …

Many pharmaceutical drugs in the marketplace and discovery pipeline suffer from poor
aqueous solubility, thereby limiting their effectiveness for oral delivery. The use of an …

Amorphous solid dispersion (ASD) can accelerate a project by improving dissolution rate
and solubility, offering dose escalation flexibility and excipient acceptance for toxicology …

Amorphous solid dispersions are considered a promising formulation strategy for the oral
delivery of poorly soluble drugs. The limiting factor for the applicability of this approach is the …

Amorphous solid dispersions (ASDs) are a formulation and development strategy that can
be used to increase the apparent aqueous solubility of poorly water-soluble drugs. Their …

Amorphous solid dispersion (ASD) formulations are routinely used to enable the delivery of
poorly soluble compounds. This type of formulations can enhance bioavailability due to …

Amorphous solid dispersions (ASDs) of a poorly water-soluble active pharmaceutical
ingredient (API) in a polymer matrix can enhance the water solubility and therefore generally …