[HTML][HTML] Multi-walled carbon nanotubes elicit concordant changes in DNA methylation and gene expression following long-term pulmonary exposure in mice
G Scala, MN Delaval, SP Mukherjee, A Federico… - Carbon, 2021 - Elsevier
Pulmonary exposure to multi-walled carbon nanotubes (MWCNTs) causes inflammation and
fibrosis. Our previous work has shown that industrially produced MWCNTs trigger specific …
fibrosis. Our previous work has shown that industrially produced MWCNTs trigger specific …
Alterations in DNA methylation corresponding with lung inflammation and as a biomarker for disease development after MWCNT exposure
TA Brown, JW Lee, A Holian, V Porter… - …, 2016 - Taylor & Francis
Use of multi-walled carbon nanotubes (MWCNT) is growing which increases occupational
exposures to these materials. Their toxic potential makes it important to have an in-depth …
exposures to these materials. Their toxic potential makes it important to have an in-depth …
Multiwalled carbon nanotubes of varying size lead to DNA methylation changes that correspond to lung inflammation and injury in a mouse model
E Cole, JL Ray, S Bolten, RF Hamilton Jr… - Chemical Research …, 2019 - ACS Publications
Diversity in physicochemical properties of engineered multiwalled carbon nanotubes
(MWCNTs) increases the complexity involved in interpreting toxicity studies of these …
(MWCNTs) increases the complexity involved in interpreting toxicity studies of these …
[HTML][HTML] Single-walled and multi-walled carbon nanotubes induce sequence-specific epigenetic alterations in 16 HBE cells
Recent studies have identified carbon nanotube (CNT)-induced epigenetic changes as one
of the key players in patho-physiological response. In the present study, we investigated …
of the key players in patho-physiological response. In the present study, we investigated …
DNA methylation changes in human lung epithelia cells exposed to multi-walled carbon nanotubes
Humans are increasingly exposed to nanoparticles and, although many of their
physiological effects have been described, the molecular mechanisms underlying them are …
physiological effects have been described, the molecular mechanisms underlying them are …
[HTML][HTML] Toxicogenomics analysis of dynamic dose-response in macrophages highlights molecular alterations relevant for multi-walled carbon nanotube-induced lung …
Toxicogenomics approaches are increasingly used to gain mechanistic insight into the
toxicity of engineered nanomaterials (ENMs). These emerging technologies have been …
toxicity of engineered nanomaterials (ENMs). These emerging technologies have been …
Differences in MWCNT-and SWCNT-induced DNA methylation alterations in association with the nuclear deposition
Background Subtle DNA methylation alterations mediated by carbon nanotubes (CNTs)
exposure might contribute to pathogenesis and disease susceptibility. It is known that both …
exposure might contribute to pathogenesis and disease susceptibility. It is known that both …
Comparative analysis of lung and blood transcriptomes in mice exposed to multi-walled carbon nanotubes
TO Khaliullin, N Yanamala, MS Newman… - Toxicology and applied …, 2020 - Elsevier
Pulmonary exposure to multi-walled carbon nanotubes (MWCNT) causes inflammation,
fibroproliferation, immunotoxicity, and systemic responses in rodents. However, the search …
fibroproliferation, immunotoxicity, and systemic responses in rodents. However, the search …
Postchronic single-walled carbon nanotube exposure causes irreversible malignant transformation of human bronchial epithelial cells through DNA methylation …
J Wang, X Tian, J Zhang, L Tan, N Ouyang, B Jia… - ACS …, 2021 - ACS Publications
As environmental pollutants and possible carcinogens, carbon nanotubes (CNTs) have
recently been found to induce carcinogenesis and tumor metastasis after long-term …
recently been found to induce carcinogenesis and tumor metastasis after long-term …
Multi-walled carbon nanotube-induced gene expression in the mouse lung: association with lung pathology
M Pacurari, Y Qian, DW Porter, M Wolfarth… - Toxicology and applied …, 2011 - Elsevier
Due to the fibrous shape and durability of multi-walled carbon nanotubes (MWCNT),
concerns regarding their potential for producing environmental and human health risks …
concerns regarding their potential for producing environmental and human health risks …
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