[HTML][HTML] Multi-walled carbon nanotubes elicit concordant changes in DNA methylation and gene expression following long-term pulmonary exposure in mice

G Scala, MN Delaval, SP Mukherjee, A Federico… - Carbon, 2021 - Elsevier
Pulmonary exposure to multi-walled carbon nanotubes (MWCNTs) causes inflammation and
fibrosis. Our previous work has shown that industrially produced MWCNTs trigger specific …

Alterations in DNA methylation corresponding with lung inflammation and as a biomarker for disease development after MWCNT exposure

TA Brown, JW Lee, A Holian, V Porter… - …, 2016 - Taylor & Francis
Use of multi-walled carbon nanotubes (MWCNT) is growing which increases occupational
exposures to these materials. Their toxic potential makes it important to have an in-depth …

Multiwalled carbon nanotubes of varying size lead to DNA methylation changes that correspond to lung inflammation and injury in a mouse model

E Cole, JL Ray, S Bolten, RF Hamilton Jr… - Chemical Research …, 2019 - ACS Publications
Diversity in physicochemical properties of engineered multiwalled carbon nanotubes
(MWCNTs) increases the complexity involved in interpreting toxicity studies of these …

[HTML][HTML] Single-walled and multi-walled carbon nanotubes induce sequence-specific epigenetic alterations in 16 HBE cells

M Ghosh, D Öner, RC Duca, B Bekaert… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Recent studies have identified carbon nanotube (CNT)-induced epigenetic changes as one
of the key players in patho-physiological response. In the present study, we investigated …

DNA methylation changes in human lung epithelia cells exposed to multi-walled carbon nanotubes

MI Sierra, L Rubio, GF Bayón, I Cobo… - …, 2017 - Taylor & Francis
Humans are increasingly exposed to nanoparticles and, although many of their
physiological effects have been described, the molecular mechanisms underlying them are …

[HTML][HTML] Toxicogenomics analysis of dynamic dose-response in macrophages highlights molecular alterations relevant for multi-walled carbon nanotube-induced lung …

LA Saarimäki, PAS Kinaret, G Scala, G del Giudice… - NanoImpact, 2020 - Elsevier
Toxicogenomics approaches are increasingly used to gain mechanistic insight into the
toxicity of engineered nanomaterials (ENMs). These emerging technologies have been …

Differences in MWCNT-and SWCNT-induced DNA methylation alterations in association with the nuclear deposition

D Öner, M Ghosh, H Bové, M Moisse, B Boeckx… - Particle and fibre …, 2018 - Springer
Background Subtle DNA methylation alterations mediated by carbon nanotubes (CNTs)
exposure might contribute to pathogenesis and disease susceptibility. It is known that both …

Comparative analysis of lung and blood transcriptomes in mice exposed to multi-walled carbon nanotubes

TO Khaliullin, N Yanamala, MS Newman… - Toxicology and applied …, 2020 - Elsevier
Pulmonary exposure to multi-walled carbon nanotubes (MWCNT) causes inflammation,
fibroproliferation, immunotoxicity, and systemic responses in rodents. However, the search …

Postchronic single-walled carbon nanotube exposure causes irreversible malignant transformation of human bronchial epithelial cells through DNA methylation …

J Wang, X Tian, J Zhang, L Tan, N Ouyang, B Jia… - ACS …, 2021 - ACS Publications
As environmental pollutants and possible carcinogens, carbon nanotubes (CNTs) have
recently been found to induce carcinogenesis and tumor metastasis after long-term …

Multi-walled carbon nanotube-induced gene expression in the mouse lung: association with lung pathology

M Pacurari, Y Qian, DW Porter, M Wolfarth… - Toxicology and applied …, 2011 - Elsevier
Due to the fibrous shape and durability of multi-walled carbon nanotubes (MWCNT),
concerns regarding their potential for producing environmental and human health risks …