[HTML][HTML] Apolipoprotein B-containing lipoprotein assembly in microsomal triglyceride transfer protein-deficient McA-RH7777 cells
Y Liu, M Manchekar, Z Sun, PE Richardson… - Journal of lipid …, 2010 - ASBMB
Microsomal triglyceride transfer protein (MTP) is required for the assembly and secretion of
apolipoprotein (apo) B-containing lipoproteins. Previously, we demonstrated that the N …
apolipoprotein (apo) B-containing lipoproteins. Previously, we demonstrated that the N …
[HTML][HTML] Microsomal triglyceride transfer protein activity is not required for the initiation of apolipoprotein B-containing lipoprotein assembly in McA-RH7777 cells
N Dashti, M Manchekar, Y Liu, Z Sun… - Journal of Biological …, 2007 - ASBMB
We previously demonstrated that the N-terminal 1000 amino acid residues of human
apolipoprotein (apo) B (designated apoB: 1000) are competent to fold into a three-sided …
apolipoprotein (apo) B (designated apoB: 1000) are competent to fold into a three-sided …
Progress towards understanding the role of microsomal triglyceride transfer protein in apolipoprotein-B lipoprotein assembly
DA Gordon, H Jamil - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2000 - Elsevier
The microsomal triglyceride transfer protein (MTP) is necessary for the proper assembly of
the apolipoprotein B containing lipoproteins, very low density lipoprotein and chylomicrons …
the apolipoprotein B containing lipoproteins, very low density lipoprotein and chylomicrons …
[HTML][HTML] The microsomal triglyceride transfer protein facilitates assembly and secretion of apolipoprotein B-containing lipoproteins and decreases cotranslational …
We studied the role of microsomal triglyceride transfer protein (MTP) in the synthesis,
secretion, and cotranslational degradation of apolipoprotein (apo) B using nonhepatic COS …
secretion, and cotranslational degradation of apolipoprotein (apo) B using nonhepatic COS …
[HTML][HTML] Generation of hepatoma cell lines deficient in microsomal triglyceride transfer protein
The microsomal triglyceride transfer protein (MTP) is essential for the secretion of
apolipoprotein B (apoB) 48-and apoB100-containing lipoproteins in the intestine and liver …
apolipoprotein B (apoB) 48-and apoB100-containing lipoproteins in the intestine and liver …
[HTML][HTML] Identification of a novel isoform of microsomal triglyceride transfer protein
Microsomal triglyceride transfer protein (MTP) has been studied extensively, primarily
because of its role in the assembly of very low density lipoproteins by the liver and …
because of its role in the assembly of very low density lipoproteins by the liver and …
[HTML][HTML] Inhibition of the microsomal triglyceride transfer protein blocks the first step of apolipoprotein B lipoprotein assembly but not the addition of bulk core lipids in …
DA Gordon, H Jamil, RE Gregg, SO Olofsson… - Journal of Biological …, 1996 - ASBMB
The microsomal triglyceride transfer protein (MTP) is required for assembly and secretion of
the lipoproteins containing apolipoprotein B (apoB): very low density lipoproteins and …
the lipoproteins containing apolipoprotein B (apoB): very low density lipoproteins and …
[HTML][HTML] The activity of microsomal triglyceride transfer protein is essential for accumulation of triglyceride within microsomes in McA-RH7777 cells: a unified model for …
Y Wang, K Tran, Z Yao - Journal of Biological Chemistry, 1999 - ASBMB
Previously, based on distinct requirement of microsomal triglyceride transfer protein (MTP)
and kinetics of triglyceride (TG) utilization, we concluded that assembly of very low density …
and kinetics of triglyceride (TG) utilization, we concluded that assembly of very low density …
[HTML][HTML] Evidence that microsomal triglyceride transfer protein is limiting in the production of apolipoprotein B-containing lipoproteins in hepatic cells
H Jamil, CH Chu, JK Dickson, Y Chen, M Yan… - Journal of lipid …, 1998 - ASBMB
The microsomal triglyceride transfer protein (MTP) is a heterodimeric lipid transfer protein
that is required for the assembly and secretion of apolipoprotein B (apoB)-containing …
that is required for the assembly and secretion of apolipoprotein B (apoB)-containing …
[HTML][HTML] Chinese hamster ovary cells require the coexpression of microsomal triglyceride transfer protein and cholesterol 7α-hydroxylase for the assembly and …
JF Fleming, GM Spitsen, TY Hui, L Olivier, EZ Du… - Journal of Biological …, 1999 - ASBMB
Due to the absence of microsomal triglyceride transfer protein (MTP), Chinese hamster
ovary (CHO) cells lack the ability to translocate apoB into the lumen of the endoplasmic …
ovary (CHO) cells lack the ability to translocate apoB into the lumen of the endoplasmic …