Differences in pituitary adenylate cyclase-activating peptide and calcitonin gene-related peptide release in the trigeminovascular system
JCA Edvinsson, AS Grell, K Warfvinge… - …, 2020 - journals.sagepub.com
Background Several neurotransmitters are expressed in the neurons of the trigeminal
ganglion. One such signalling molecule is the pituitary adenylate cyclase-activating peptide …
ganglion. One such signalling molecule is the pituitary adenylate cyclase-activating peptide …
Shared and independent roles of CGRP and PACAP in migraine pathophysiology
A Kuburas, AF Russo - The Journal of Headache and Pain, 2023 - Springer
The neuropeptides calcitonin gene-related peptide (CGRP) and pituitary adenylate cyclase-
activating polypeptide (PACAP) have emerged as mediators of migraine pathogenesis. Both …
activating polypeptide (PACAP) have emerged as mediators of migraine pathogenesis. Both …
Dynamic changes in CGRP, PACAP, and PACAP receptors in the trigeminovascular system of a novel repetitive electrical stimulation rat model: Relevant to migraine
Q Zhang, X Han, H Wu, M Zhang, G Hu… - Molecular …, 2019 - journals.sagepub.com
Migraine is the seventh most disabling disorder globally, with prevalence of 11.7%
worldwide. One of the prevailing mechanisms is the activation of the trigeminovascular …
worldwide. One of the prevailing mechanisms is the activation of the trigeminovascular …
Expression of pituitary adenylate cyclase-activating peptide, calcitonin gene-related peptide and headache targets in the trigeminal ganglia of rats and humans
SD Frederiksen, K Warfvinge, L Ohlsson, L Edvinsson - Neuroscience, 2018 - Elsevier
Neurotransmitter and headache target localization in the trigeminal ganglia (TG) might
increase the understanding of sites of action, and mechanisms related to headache therapy …
increase the understanding of sites of action, and mechanisms related to headache therapy …
Pituitary adenylate cyclase‐activating polypeptide receptors in the trigeminovascular system: implications for migraine
T Sundrum, CS Walker - British journal of pharmacology, 2018 - Wiley Online Library
The neuropeptide pituitary adenylate cyclase‐activating polypeptide (PACAP) has been
implicated in a wide range of functions including vasodilatation, neuroprotection …
implicated in a wide range of functions including vasodilatation, neuroprotection …
The PACAP receptor: a novel target for migraine treatment
The origin of migraine pain has not yet been clarified, but accumulating data point to
neuropeptides present in the perivascular space of cranial vessels as important mediators of …
neuropeptides present in the perivascular space of cranial vessels as important mediators of …
Inhibiting PAC1 receptor internalization and endosomal ERK pathway activation may ameliorate hyperalgesia in a chronic migraine rat model
L Zhang, Y Zhou, Y Wang, L Yang, Y Wang… - …, 2023 - journals.sagepub.com
Background Pituitary adenylate cyclase-activating polypeptide (PACAP) is a multipotent
neuropeptide widely distributed in the trigeminovascular system (TVS) and higher brain …
neuropeptide widely distributed in the trigeminovascular system (TVS) and higher brain …
Temporal alterations of pituitary adenylate cyclase activating polypeptide and its receptors in a rat model induced by recurrent chemical stimulations: Relevant to …
H Wu, Z Dong, Y Liu, Q Zhang, M Zhang… - Molecular …, 2023 - journals.sagepub.com
Background: Migraine is a common type of primary headache with disabling brain
dysfunction. It has been found that pituitary adenylate cyclase activating polypeptide …
dysfunction. It has been found that pituitary adenylate cyclase activating polypeptide …
Role of pituitary adenylate cyclase-activating polypeptide in nociception and migraine
J Tajti, B Tuka, B Botz, Z Helyes… - CNS & Neurological …, 2015 - ingentaconnect.com
Pituitary adenylate cyclase-activating polypeptide (PACAP) and its receptors are widely
distributed at different levels of the pain-processing pathway. Its action at the peripheral …
distributed at different levels of the pain-processing pathway. Its action at the peripheral …
Pituitary adenylate cyclase activating polypeptide and migraine
AS Zagami, L Edvinsson… - Annals of clinical and …, 2014 - Wiley Online Library
Pituitary adenylate cyclase activating peptide (PACAP) is found in human trigeminocervical
complex and can trigger migraine. PACAP levels were measured using a sensitive …
complex and can trigger migraine. PACAP levels were measured using a sensitive …
相关搜索
- pituitary adenylate peptide release
- pituitary adenylate implications for migraine
- pituitary adenylate polypeptide receptors
- pituitary adenylate trigeminal ganglia
- pituitary adenylate rats and humans
- chronic migraine adenylate cyclase
- chemical stimulations adenylate cyclase
- temporal alterations adenylate cyclase