Captopril (50 mg orally) produced a significant fall in systolic and diastolic blood pressure in
six normotensive sodium replete subjects, without a rise in heart rate. On captopril, there …

1 The effect of captopril on autonomic reflex functions has been investigated in fifteen
patients with essential hypertension by examining their responses to tests of baroreceptor …

Angiotensin converting enzyme inhibitors reduce blood pressure without reflex tachycardia,
possibly as a result of enhanced hypothesis that this results from the removal of the …

The present study was conducted to investigate the influence of captopril on
cardiochemodynamic responses in 38 normal volunteers (20-to 35-year-old men) to …

The effect of the converting enzyme inhibitor captopril on arterial pressure, the components
of the renin-angiotensin-aldosterone system, and body sodium and potassium content was …

Twenty-four patients with moderate to severe hypertension were treated for four weeks with
captopril, an oral inhibitor of angiotensin-converting enzyme. The fall in blood pressure with …

Captopril and propranolol were given alone and in combination to 13 hypertensive men and
the effects studied at rest (seated, supine and standing) and during exercise. The two drugs …

Twenty severely hypertensive subjects who did not achieve blood pressure control with
combination therapy with a vasodilator, a beta-adrenergic blocking agent and a diuretic …

Because captopril alone does not control blood pressure in all patients with essential
hypertension, studies were performed to assess the effect of sodium intake and of captopril …

Captopril was given to 15 unselected patients with essential hypertension (WHO II) at a dose
range of 300 to 600 mg/day. Hemodynamic indexes (thermodilution) as well as levels of …