The antihypertensive effects of captopril and enalapril maleate were studied over a 10-week
period in 24 hypertensive patients randomized into captopril or enalapril treatment groups …

1. Captopril infused into sodium-loaded dogs produced a fall in both blood pressure [117+/-
9.7 to 96.6+/-11.4 (SD) mmHg] and plasma angiotensin II [11.0+/-3.0 to 1.6+/-1.3 (SD) …

1. The acute effects of a single oral dose of captopril on blood pressure, pulse rate and
circulating levels of angiotensin I (ANG I), angiotensin II (ANG II), renin, bradykinin and …

1. Central effects of single doses of captopril (12.5, 25 and 50 mg) were studied in fourteen
healthy male subjects. Two placebos and an active control drug, oxazepam (15 mg), were …

Captopril inhibits angiotensin II formation and bradykinin degradation in vivo. Eleven
patients with essential hypertension (EH) and four patients with renovascular hypertension …

Absent reflex tachycardia with captopril therapy suggests blunting of circulatory reflexes,
perhaps contributing to antihypertensive efficacy, and angiotensin converting enzyme …

Nine patients with uncomplicated essential hypertension received, according to a
randomized sequence, captopril (25 mg three times daily), nifedipine (10 mg three times …

The blood pressure response to the first dose of captopril (6.25 mg, 12.5 mg, or 25 mg) was
measured in 65 treated, severely hypertensive patients. Mean supine blood pressure was …

Twenty sodium-replete patients with hypertension were allocated either to a placebo or to a
captopril treatment group. Each patient was investigated in rest-recumbent (RR) and rest …

The anglotensin converting enzyme inhibitor captopril improves the altered hemodynamics
in many patients with chronic heart failure, but the first dose may precipitate hypotension …