Efficacy of an oral angiotensin-converting enzyme inhibitor (captopril) in severe hypertension

AJ Zweifler, S Julius, MG Nicholls - Archives of Internal Medicine, 1981 - jamanetwork.com
• The antihypertensive effect of captopril was assessed during short-and long-term periods
in ten patients with elevated blood pressure readings that were uncontrollable by standard …

Captopril: evaluation of low doses, twice-daily doses and the addition of diuretic for the treatment of mild to moderate hypertension

Veterans Administration Cooperative Study … - Clinical …, 1982 - portlandpress.com
1. We randomized 475 men whose diastolic blood pressure was 92–109 mmHg to either
placebo-or captopril-treated (37.5, 75 and 150 mg/day) groups for 7 weeks. 2. After 7 weeks …

Acute and chronic systemic and pulmonary hemodynamic effects of angiotensin converting enzyme inhibition with captopril in hypertensive patients

R Fagard, A Amery, T Reybrouck, P Lijnen… - The American journal of …, 1980 - Elsevier
The effects of the angiotensin converting enzyme inhibitor captopril were studied in 14
patients with essential or renovascular hypertension 75 minutes after ingestion of 25 mg of …

Acute and chronic effects of the converting enzyme inhibitors enalapril and lisinopril on reflex control of heart rate in normotensive man

AA Ajayi, BC Campbell, CA Howie… - Journal of …, 1985 - journals.lww.com
The effects of enalapril maleate and its lysine analogue, lisinopril, on reflex control of heart
rate after acute and chronic administration were examined in 10 normotensive males. Both …

Sequential changes in circulating levels of angiotensin I and II, renin, and bradykinin after captopril

JA Millar, CI Johnston - Medical Journal of Australia, 1979 - Wiley Online Library
Venous blood levels of angiotensin I, angiotensin II, bradykinin and renin were measured
before, and 30, 60, 90 and 120 minutes after, the administration of Captopril (50 mg) to eight …

Acute effects of captopril on the coronary circulation of patients with hypertension and angina

P Daly, JL Rouleau, D Cousineau… - The American journal of …, 1984 - Elsevier
Patients with hypertension have a high incidence of coronary artery disease. Captopril, the
angiotensin-converting enzyme inhibitor, was given to eight patients with hypertension and …

Additive effect of isradipine in combination with captopril in hypertensive patients

R Eggertsen, A Svensson, B Dahlöf… - The American Journal of …, 1989 - Elsevier
The effects of combined treatment with the calcium antagonist isradipine and the
angiotensin-converting enzyme inhibitor captopril were investigated in a randomized …

Acute and chronic treatment of severe and malignant hypertension with the oral angiotensin-converting enzyme inhibitor captopril.

DB Case, SA Atlas, PA Sullivan, JH Laragh - Circulation, 1981 - Am Heart Assoc
The patients with severe and 10 with accelerated or malignant hypertension were treated
with the angiotensin-converting enzyme inhibitor captopril. Captopril acutely reduced blood …

Low-dose captopril titration in patients with moderate-to-severe hypertension treated with diuretics.

GS Thind, RK Mahapatra, A Johnson, RD Coleman - Circulation, 1983 - Am Heart Assoc
To study the value of low-dose captopril (6.25 and 12.5 mg) and a diuretic combination, the
blood pressure and heart rate of 17 patients with moderate-to-severe hypertension were …

Hypotensive effect of captopril. Role of bradykinin and prostaglandinlike substances.

V Pontieri, OU Lopes, SH Ferreira - Hypertension, 1990 - Am Heart Assoc
Captopril (0.15-10 mg/kg) administration in the anesthetized dog causes immediate
hypotension concomitant with an increase in tonus of the assay tissue (cat terminal ileum) …