Hypotensive action of captopril in spontaneously hypertensive and normotensive rats. Interference with neurogenic vasoconstriction.

DP Clough, R Hatton, JR Keddie, MG Collis - Hypertension, 1982 - Am Heart Assoc
The effects of captopril and angiotensin II on adrenergic neurotransmission have been
studied in spontaneously hypertensive rats (SHR) and Wistar-Kyoto rats (WKY). In a pithed …

Captopril and atenolol combined with hydrochlorothiazide in essential hypertension.

L Andrén, B Karlberg, P Ohman… - British Journal of …, 1982 - Wiley Online Library
1 Fifty‐seven patients with mild or moderate essential hypertension, mean age 50 (range 31‐
69) were randomised to treatment with either captopril or atenolol. Twenty‐six patients in …

Lack of relationship between the short-term hemodynamic effects of captopril and subsequent clinical responses.

BM Massie, BL Kramer, N Topic - Circulation, 1984 - Am Heart Assoc
The role of hemodynamic monitoring during the initiation of vasodilator therapy for heart
failure remains to be defined, despite the tremendous potential socioeconomic and clinical …

Hemodynamic and hormonal responses during captopril therapy for heart failure: acute, chronic and withdrawal studies

MG Nicholls, H Ikram, EA Espiner, AH Maslowski… - The American Journal of …, 1982 - Elsevier
The hemodynamic and hormonal responses to acute and chronic captopril therapy and to its
temporary withdrawal were studied in seven patients with congestive heart failure. Maximal …

Influence of food on acute and chronic effects of captopril in essential hypertensive patients

A Salvetti, R Pedrinelli, A Magagna… - Journal of …, 1985 - journals.lww.com
To determine if food reduces the hemodynamic and humoral effects of captopril in patients
with essential hypertension, we performed two studies. In the acute study, 15 inpatients with …

Acute and chronic effects of the angiotensin-converting enzyme inhibitor captopril in severe hypertension

J Havelka, H Vetter, A Studer, P Greminger… - The American Journal of …, 1982 - Elsevier
In this study the acute and chronic effect of the converting enzyme inhibitor captopril was
investigated in a relatively large number of patients (acute: n= 78, chronic: n= 67) with …

The effect of captopril on catecholamines, renin activity, angiotensin II and aldosterone in plasma during physical exercise in hypertensive patients

P Manhem, M Bramnert, UL Hulthén… - European Journal of …, 1981 - Wiley Online Library
The studies were designed to explore the effect of the converting enzyme inhibitor captopril
on the activity of the sympathetic nervous system during basal conditions and following …

Captopril: a preliminary review of its pharmacological properties and therapeutic efficacy

RC Heel, RN Brogden, TM Speight, GS Avery - Drugs, 1980 - Springer
Synopsis: Captopril 1 is the first orally active inhibitor of angiotensin-converting enzyme to
become available. It has been studied to date primarily in hypertension. In mild to moderate …

Mood changes during captopril therapy for hypertension. A double-blind pilot study.

JS Callender, GP Hodsman, MJ Hutcheson… - …, 1983 - Am Heart Assoc
A small double-blind pilot study was carried out to assess whether captopril treatment in
hypertension has a euphoriant effect. Eight patients were maintained on constant therapy of …

Hemodynamic and volume changes associated with captopril.

RC Tarazi, EL Bravo, FM Fouad, P Omvik… - Hypertension, 1980 - Am Heart Assoc
The effects of captopril on bemodynamic, rolmne, and neurohumoral indices were
inrestigated in 33 patients with essential hypertension or renal arterial disease. Changes …