Error-related brain activity as a transdiagnostic endophenotype for obsessive-compulsive disorder, anxiety and substance use disorder

A Riesel, J Klawohn, R Grützmann… - Psychological …, 2019 - cambridge.org
BackgroundIncreased neural error-signals have been observed in obsessive-compulsive
disorder (OCD), anxiety disorders, and inconsistently in depression. Reduced neural error …

Increased error‐related brain activity in youth with obsessive‐compulsive disorder and unaffected siblings

M Carrasco, SM Harbin, JK Nienhuis… - Depression and …, 2013 - Wiley Online Library
Background The pathophysiology of obsessive‐compulsive disorder (OCD) involves
increased activity in cortico‐striatal circuits connecting the anterior cingulate cortex (ACC) …

Overactive error-related brain activity as a candidate endophenotype for obsessive-compulsive disorder: evidence from unaffected first-degree relatives

A Riesel, T Endrass, C Kaufmann… - American Journal of …, 2011 - Am Psychiatric Assoc
Objective: Hyperactivity in frontal-striatal circuits is assumed to be involved in the
pathophysiology of obsessive-compulsive disorder (OCD). In line with that, electrocortical …

Neural markers of errors as endophenotypes in neuropsychiatric disorders

DS Manoach, Y Agam - Frontiers in human neuroscience, 2013 - frontiersin.org
Learning from errors is fundamental to adaptive human behavior. It requires detecting errors,
evaluating what went wrong, and adjusting behavior accordingly. These dynamic …

The erring brain: Error‐related negativity as an endophenotype for OCD—A review and meta‐analysis

A Riesel - Psychophysiology, 2019 - Wiley Online Library
Obsessive‐compulsive disorder (OCD) is a complex and heterogeneous disorder that is
associated with high personal and societal costs. Feelings of doubt, worry, and repetitive …

Error-related brain activity in patients with obsessive-compulsive disorder and in healthy controls

M Ruchsow, G Grön, K Reuter… - Journal of …, 2005 - econtent.hogrefe.com
Obsessive-compulsive disorder (OCD) has been related to a hyperactive frontal-striatal-
thalamic circuit and associated with altered mechanisms of action and error monitoring. In …

Error-related brain activity in youth and young adults before and after treatment for generalized or social anxiety disorder

A Kujawa, A Weinberg, N Bunford, KD Fitzgerald… - Progress in Neuro …, 2016 - Elsevier
Increased error monitoring, as measured by the error-related negativity (ERN), has been
shown to persist after treatment for obsessive-compulsive disorder in youth and adults; …

Altered cingulate sub-region activation accounts for task-related dissociation in ERN amplitude as a function of obsessive-compulsive symptoms

JF Cavanagh, TOJ Gründler, MJ Frank, JJB Allen - Neuropsychologia, 2010 - Elsevier
Larger error-related negativities (ERNs) have been consistently found in obsessive-
compulsive disorder (OCD) patients, and are thought to reflect the activities of a hyperactive …

Error-related negativity and tic history in pediatric obsessive-compulsive disorder

GL Hanna, M Carrasco, SM Harbin, JK Nienhuis… - Journal of the American …, 2012 - Elsevier
OBJECTIVE: The error-related negativity (ERN) is a negative deflection in the event-related
potential after an incorrect response, which is often increased in patients with obsessive …

Error-related negativity abnormalities in generalized anxiety disorder and obsessive–compulsive disorder

Z Xiao, J Wang, M Zhang, H Li, Y Tang, Y Wang… - Progress in Neuro …, 2011 - Elsevier
Enhanced error-related negativity (ERN) has been associated with anxiety among both non-
clinical and clinical populations. However, whether it is abnormal among adult patients with …