Associations between dopamine D2 receptor availability and BMI depend on age
Objective The dopamine D2/3 receptor subtypes (DRD2/3) are the most widely studied
neurotransmitter biomarker in research on obesity, but results to date have been …
neurotransmitter biomarker in research on obesity, but results to date have been …
[HTML][HTML] Elevated dopamine D2/3 receptor availability in obese individuals: a PET imaging study with [11C](+) PHNO
EC Gaiser, JD Gallezot, PD Worhunsky… - …, 2016 - nature.com
Most prior work with positron emission tomography (PET) dopamine subtype 2/3 receptor (D
2/3 R) non-selective antagonist tracers suggests that obese (OB) individuals exhibit lower D …
2/3 R) non-selective antagonist tracers suggests that obese (OB) individuals exhibit lower D …
[HTML][HTML] Lower striatal dopamine D2/3 receptor availability in obese compared with non-obese subjects
BA de Weijer, E van de Giessen, TA van Amelsvoort… - EJNMMI research, 2011 - Springer
Background Obesity is a result of a relative excess in energy intake over energy
expenditure. These processes are controlled by genetic, environmental, psychological and …
expenditure. These processes are controlled by genetic, environmental, psychological and …
Low dopamine striatal D2 receptors are associated with prefrontal metabolism in obese subjects: possible contributing factors
Dopamine's role in inhibitory control is well recognized and its disruption may contribute to
behavioral disorders of discontrol such as obesity. However, the mechanism by which …
behavioral disorders of discontrol such as obesity. However, the mechanism by which …
No association between striatal dopamine transporter binding and body mass index: a multi-center European study in healthy volunteers
INTRODUCTION: Dopamine is one among several neurotransmitters that regulate food
intake and overeating. Thus, it has been linked to the pathophysiology of obesity and high …
intake and overeating. Thus, it has been linked to the pathophysiology of obesity and high …
Striatal dopamine D2-like receptor correlation patterns with human obesity and opportunistic eating behavior
The obesity epidemic is believed to be driven by a food environment that promotes
consumption of inexpensive, convenient, high-calorie, palatable foods. Individual …
consumption of inexpensive, convenient, high-calorie, palatable foods. Individual …
Ventral striatum binding of a dopamine D2/3 receptor agonist but not antagonist predicts normal body mass index
Background Positron emission tomography research has shown that dopamine D 2/3
receptor (D 2/3 R) availability is negatively correlated with body mass index (BMI) in obese …
receptor (D 2/3 R) availability is negatively correlated with body mass index (BMI) in obese …
[HTML][HTML] Striatal dopamine D2-like receptors availability in obesity and its modulation by bariatric surgery: A systematic review and meta-analysis
G Ribeiro, A Maia, G Cotovio, FPM Oliveira… - Scientific Reports, 2023 - nature.com
There is significant evidence linking a 'reward deficiency syndrome'(RDS), comprising
decreased availability of striatal dopamine D2-like receptors (DD2lR) and addiction-like …
decreased availability of striatal dopamine D2-like receptors (DD2lR) and addiction-like …
Modulation of striatal dopamine D1 binding by cognitive processing
There is strong evidence that dopamine (DA) is implicated in higher-order cognitive
functioning, but it remains controversial whether D1 receptor binding can be modified by …
functioning, but it remains controversial whether D1 receptor binding can be modified by …
Relationship of dopamine type 2 receptor binding potential with fasting neuroendocrine hormones and insulin sensitivity in human obesity
JP Dunn, RM Kessler, ID Feurer, ND Volkow… - Diabetes …, 2012 - Am Diabetes Assoc
OBJECTIVE Midbrain dopamine (DA) neurons, which are involved with reward and
motivation, are modulated by hormones that regulate food intake (insulin, leptin, and acyl …
motivation, are modulated by hormones that regulate food intake (insulin, leptin, and acyl …