This is a striking article in the Lancet's series," Hypothesis", from the, Department of
Epidemiology, Harvard and the Department of Neurology, Newcastle-upon-Tyne. It presents …

The oversimplified but commonly accepted belief, based on the comparison of the
prevalence studies conducted until 1980, that the distribution of multiple sclerosis (MS) in …

(Fig. 5). By about 1980 white women had higher death rates in the US at all ages (Fig. 6). All
these findings suggest a cohort effect for changing sex ratios over time. We have been …

THE FREQUENCY of multiple sclerosis increases with latitude both in the northern 1-15 and
southern hemisphere. 16, 17 Ethnic differences apparently do not account for this peculiar …

A review of multiple sclerosis (MS) case reports, using the unified record system at the Mayo
Clinic for the Olmsted County population, revealed age-and sex-adjusted prevalence rates …

Although the cause of multiple sclerosis (MS) is unknown, epidemiologic studies support
both genetic and environmental components of susceptibility. Reports of clusters, small …

Parts of the United Kingdom have the highest incidence, prevalence and mortality rates for
multiple sclerosis in the world. Although methods of ascertainment are not standardised …

Existing data on the incidence of multiple sclerosis (MS) in the UK have some limitations.
Few studies have reported age-and sex-specific incidence rates of MS, and none of those is …

MULTIPLE sclerosis tends to be common in temperate latitudes and rare in regions near the
equator. 1-4 This geographical distribution suggests that some factor in temperate …

A national survey, sponsored by the National Institute of Neurological and Communicative
Disorders and Stroke, to determine the incidence, prevalence, and economic impact of …