Elevated cerebrospinal fluid and blood concentrations of oxytocin following its intranasal administration in humans

N Striepens, KM Kendrick, V Hanking, R Landgraf… - Scientific reports, 2013 - nature.com
There has been an unprecedented interest in the modulatory effects of intranasal oxytocin
on human social cognition and behaviour, however as yet no study has actually …

Advances in the field of intranasal oxytocin research: lessons learned and future directions for clinical research

DS Quintana, A Lischke, S Grace, D Scheele… - Molecular …, 2021 - nature.com
Reports on the modulatory role of the neuropeptide oxytocin on social cognition and
behavior have steadily increased over the last two decades, stimulating considerable …

Sniffing oxytocin: Nose to brain or nose to blood?

S Yao, Y Chen, Q Zhuang, Y Zhang, C Lan, S Zhu… - Molecular …, 2023 - nature.com
In recent years ample studies have reported that intranasal administration of the
neuropeptide oxytocin can facilitate social motivation and cognition in healthy and clinical …

Plasma and CSF oxytocin levels after intranasal and intravenous oxytocin in awake macaques

SM Freeman, S Samineni, PC Allen… - …, 2016 - Elsevier
Oxytocin (OT) is a neuropeptide that mediates a variety of complex social behaviors in
animals and humans. Intranasal OT has been used as an experimental therapeutic for …

Increased brain and plasma oxytocin after nasal and peripheral administration in rats and mice

ID Neumann, R Maloumby, DI Beiderbeck… - …, 2013 - Elsevier
The possibility to improve socio-emotional behaviors in humans by intranasal administration
of synthetic oxytocin (OXT) attracts increasing attention, but its uptake into the brain has …

Intranasal oxytocin administration is reflected in human saliva

O Weisman, O Zagoory-Sharon, R Feldman - Psychoneuroendocrinology, 2012 - Elsevier
Following the discovery that intranasal administration of neuropeptides can reach the central
nervous system, a growing number of studies applied intranasal oxytocin (OT) paradigms to …

Oxytocin plasma concentrations after single intranasal oxytocin administration–a study in healthy men

A Gossen, A Hahn, L Westphal, S Prinz, RT Schultz… - Neuropeptides, 2012 - Elsevier
The neuropeptide oxytocin has become a subject of great interest in studies investigating
human social cognition. Single intranasal administration of the hormone has been reported …

Intranasal oxytocin effects on social cognition: a critique

SL Evans, O Dal Monte, P Noble, BB Averbeck - Brain research, 2014 - Elsevier
The last decade has seen a large number of published findings supporting the hypothesis
that intranasally delivered oxytocin (OT) can enhance the processing of social stimuli and …

Improving the precision of intranasal oxytocin research

A Winterton, LT Westlye, NE Steen… - Nature Human …, 2021 - nature.com
The neuropeptide oxytocin has been popularized for its role in social behaviour and
nominated as a candidate treatment for several psychiatric illnesses due to promising …

CSF and blood oxytocin concentration changes following intranasal delivery in macaque

O Dal Monte, PL Noble, J Turchi, A Cummins… - PloS one, 2014 - journals.plos.org
Oxytocin (OT) in the central nervous system (CNS) influences social cognition and behavior,
making it a candidate for treating clinical disorders such as schizophrenia and autism …