Antifungal Drug Resistance: Molecular Mechanisms in Candida albicans and Beyond
Fungal infections are a major contributor to infectious disease-related deaths across the
globe. Candida species are among the most common causes of invasive mycotic disease …
globe. Candida species are among the most common causes of invasive mycotic disease …
Molecular mechanisms governing antifungal drug resistance
Fungal pathogens are a severe public health problem. The leading causative agents of
systemic fungal infections include species from the Candida, Cryptococcus, and Aspergillus …
systemic fungal infections include species from the Candida, Cryptococcus, and Aspergillus …
Molecular evolution of antifungal drug resistance
The fungal pathogens Candida albicans, Cryptococcus neoformans, and Aspergillus
fumigatus have transitioned from a rare curiosity to a leading cause of human mortality. The …
fumigatus have transitioned from a rare curiosity to a leading cause of human mortality. The …
Emerging threats in antifungal-resistant fungal pathogens
D Sanglard - Frontiers in medicine, 2016 - frontiersin.org
The use of antifungal drugs in the therapy of fungal diseases can lead to the development of
antifungal resistance. Resistance has been described for virtually all antifungal agents in …
antifungal resistance. Resistance has been described for virtually all antifungal agents in …
Elucidating drug resistance in human fungal pathogens
Fungal pathogens cause life-threatening infections in immunocompetent and
immunocompromised individuals. Millions of people die each year due to fungal infections …
immunocompromised individuals. Millions of people die each year due to fungal infections …
Mechanisms of antifungal drug resistance
LE Cowen, D Sanglard… - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
Antifungal therapy is a central component of patient management for acute and chronic
mycoses. Yet, treatment choices are restricted because of the sparse number of antifungal …
mycoses. Yet, treatment choices are restricted because of the sparse number of antifungal …
Candida Infections, Causes, Targets, and Resistance Mechanisms: Traditional and Alternative Antifungal Agents
C Spampinato, D Leonardi - BioMed research international, 2013 - Wiley Online Library
The genus Candida includes about 200 different species, but only a few species are human
opportunistic pathogens and cause infections when the host becomes debilitated or …
opportunistic pathogens and cause infections when the host becomes debilitated or …
Emerging virulence, drug resistance and future anti-fungal drugs for Candida pathogens
V Srivastava, RK Singla… - Current topics in medicinal …, 2018 - ingentaconnect.com
Increased incidences of Candida infection have augmented morbidity and mortality in
human population, particularly among severely immunocompromised patients and those …
human population, particularly among severely immunocompromised patients and those …
Recent insights into the mechanisms of antifungal resistance
KS Barker, PD Rogers - Current infectious disease reports, 2006 - Springer
The incidence of fungal infections has increased in recent years, particularly among
immunocompromised individuals. Treatment of invasive fungal infections has been …
immunocompromised individuals. Treatment of invasive fungal infections has been …
Antifungal drug resistance among Candida species: mechanisms and clinical impact
The epidemiology of Candida infections has changed in recent years. Although Candida
albicans is still the main cause of invasive candidiasis in most clinical settings, a substantial …
albicans is still the main cause of invasive candidiasis in most clinical settings, a substantial …
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