Participation of peripheral tachykinin NK1 receptors in the carrageenan-induced inflammation of the rat temporomandibular joint

A Denadai-Souza, L de Lucca Camargo… - European Journal of …, 2009 - Elsevier
Temporomandibular disorders represent one of the major challenges in dentistry
therapeutics. This study was undertaken to evaluate the time course of carrageenan …

Nerve growth factor acts with the β2-adrenoceptor to induce spontaneous nociceptive behavior during temporomandibular joint inflammatory hyperalgesia

A Pelegrini-da-Silva, MCG Oliveira, CA Parada… - Life sciences, 2008 - Elsevier
AIMS: The aim of this study was to investigate whether the injection of nerve growth factor
induces spontaneous nociceptive behavior in the intact or sensitized temporomandibular …

[HTML][HTML] Peripheral sympathetic component of the temporomandibular joint inflammatory pain in rats

LLFR Rodrigues, MCG Oliveira, A Pelegrini-da-Silva… - The journal of pain, 2006 - Elsevier
The aim of this study was to further validate our carrageenan-induced temporomandibular
joint (TMJ) inflammatory hyperalgesia model in rats by showing that administration of …

Oral anti-hyperalgesic and anti-inflammatory activity of NK1 receptor antagonists in models of inflammatory hyperalgesia of the guinea-pig

EA Campbell, C Gentry, S Patel, B Kidd, S Cruwys… - Pain, 2000 - Elsevier
The oral analgesic and anti-inflammatory activity of NK1 antagonists with species preference
for the human receptor were assessed in (1) the carrageenan-induced inflammatory …

Activation of voltage-gated KCNQ/Kv7 channels by anticonvulsant retigabine attenuates mechanical allodynia of inflammatory temporomandibular joint in rats

W Xu, Y Wu, Y Bi, L Tan, Y Gan, KW Wang - Molecular pain, 2010 - journals.sagepub.com
Background: Temporomandibular disorders (TMDs) are characterized by persistent orofacial
pain and have diverse etiologic factors that are not well understood. It is thought that central …

Intra-articular administration of tachykinin NK1 receptor antagonists reduces hyperalgesia and cartilage destruction in the inflammatory joint in rats with adjuvant …

T Uematsu, A Sakai, H Ito, H Suzuki - European journal of pharmacology, 2011 - Elsevier
Persistent pain associated with inflammatory arthritis is an aggravating factor that decreases
patients' quality of life. Current therapies for joint pain have limited effectiveness and …

Anti-inflammatory and anti-nociceptive effects of strontium ranelate on the zymosan-induced temporomandibular joint inflammatory hypernociception in rats depend …

SM Alves, SC Abreu, JC Lemos, FIF Gomes… - Pharmacological …, 2017 - Elsevier
Background Temporomandibular joint (TMJ) disorders show inflammatory components,
heavily impacting on quality of life. Strontium ranelate has previously shown anti …

Involvement of NK-1 and NK-2 tachykinin receptor mechanisms in jaw muscle activity reflexly evoked by inflammatory irritant application to the rat temporomandibular …

M Bakke, JW Hu, BJ Sessle - Pain, 1998 - Elsevier
An electromyographic (EMG) study was carried out in 51 anesthetized rats to assess if
neurokinin, NK-1 and NK-2, receptor mechanisms and tachykinins were involved in the …

[PDF][PDF] Non-steroidal anti-inflammatory drugs attenuate hyperalgesia and block upregulation of trigeminal ganglionic sodium channel 1.7 after induction of …

BI Rui Yun, Y Ding, YH Gan - Chin J Dent Res, 2016 - cjdrcsa.com
Objective: To investigate the association between the analgesic effect of non-steroidal
antiinflammatory drugs (NSAIDs) and sodium channel 1.7 (Nav1. 7) expression in the …

Tumour necrosis factor-α mediates carrageenin-induced knee-joint incapacitation and also triggers overt nociception in previously inflamed rat knee-joints

CR Tonussi, SH Ferreira - Pain, 1999 - Elsevier
Tumour necrosis factor-α (TNFα) was studied in the carrageenin (CG) induced knee-joint
incapacitation, and also in mediating recurrent incapacitation response in knee-joints …