Effects of intra-articular ketamine on pain and somatosensory function in temporomandibular joint arthralgia patients

EE Ayesh, TS Jensen, P Svensson - PAIN®, 2008 - Elsevier
Recent studies have hypothesized that peripheral glutamate receptors could be implicated
in deep craniofacial pain conditions. In this study 18 temporomandibular joint (TMJ) …

[HTML][HTML] CENTRAL ROLE OF PROTEIN KINASE A IN PROMOTING TRIGEMINAL NOCICEPTION IN AN IN VIVO MODEL OF TEMPOROMANDIBULAR JOINT …

LK Koop, JL Hawkins, LE Cornelison… - … of oral & facial pain and …, 2017 - ncbi.nlm.nih.gov
Aims To investigate cellular changes in the spinal trigeminal nucleus (STN) and trigeminal
ganglion associated with trigeminal nociception mediated by inflammation in the …

Activation of NK1 receptor of trigeminal root ganglion via substance P paracrine mechanism contributes to the mechanical allodynia in the temporomandibular joint …

M Takeda, T Tanimoto, M Nasu, M Ikeda, J Kadoi… - Pain, 2005 - journals.lww.com
The aim of this study was to investigate whether under in vivo conditions,
temporomandibular joint (TMJ) inflammation alters the excitability of Aβ-trigeminal root …

Temporal changes in inflammatory mediator concentrations in an adjuvant model of temporomandibular joint inflammation.

R Spears, LA Dees, M Sapozhnikov… - … of orofacial pain, 2005 - search.ebscohost.com
Aims: To determine temporal changes in the concentrations found in the temporomandibular
joint (TMJ) and trigeminal ganglion of 3 specific classes of inflammatory mediators …

Local kappa opioid receptor activation decreases temporomandibular joint inflammation

TC Chicre-Alcântara, KE Torres-Chávez, L Fischer… - Inflammation, 2012 - Springer
In an attempt to decrease central side effects associated with the use of opioids, some
strategies have been developed by targeting peripheral opioid receptors. In this context …

Involvement of trigeminal ganglionic Nav1.7 in hyperalgesia of inflamed temporomandibular joint is dependent on ERK1/2 phosphorylation of glial cells in rats

RY Bi, XX Kou, Z Meng, XD Wang… - European Journal of …, 2013 - Wiley Online Library
Background Inflammation is a major cause of temporomandibular disorder‐related pain. The
N av1. 7 sodium channel has a critical function in pain perceptions. However, whether and …

An in vitro temporomandibular joint-nerve preparation for pain study in rats

Y Takeuchi, N Ishii, K Toda - Journal of neuroscience methods, 2001 - Elsevier
A novel in vitro TMJ-nerve preparation was developed to quantitatively study peripheral
sensory mechanisms of temporomandibular joint (TMJ). The TMJ region on one side …

A functional relationship between trigeminal astroglial activation and NR1 expression in a rat model of temporomandibular joint inflammation

S Wang, L Song, Y Tan, Y Ma, Y Tian, X Jin… - Pain …, 2012 - academic.oup.com
Objective To examine the hypothesis that glial activation would regulate the expression of
the N-methyl-D-aspartate receptor subunit 1 (NR1) in the trigeminal subnucleus caudalis …

[HTML][HTML] Toll-like receptor 2/MyD88 signaling mediates zymosan-induced joint hypernociception in mice: participation of TNF-α, IL-1β and CXCL1/KC

ATG Guerrero, TM Cunha, WA Verri Jr… - European journal of …, 2012 - Elsevier
Arthritic pain is a serious health problem that affects a large number of patients. Toll-like
receptors (TLRs) activation within the joints has been implicated in pathophysiology of …

Immediate effects of the serotonin antagonist granisetron on temporomandibular joint pain in patients with systemic inflammatory disorders

Ü Voog, P Alstergren, E Leibur, R Kallikorm, S Kopp - Life Sciences, 2000 - Elsevier
The aim of this study was to investigate if the 5-HT3 antagonist granisetron reduces
temporomandibular joint (TMJ) pain in patients with systemic inflammatory joint disorders …