An isobolographic analysis of the effects of N‐methyl‐D‐aspartate and NK1 tachykinin receptor antagonists on inflammatory hyperalgesia in the rat

K Ren, MJ Iadarola, R Dubner - British journal of pharmacology, 1996 - Wiley Online Library
1 The interaction between N‐methyl‐D‐aspartate (NMDA) and NK1 tachykinin receptors
was analyzed isobolographically in rats with inflammatory hyperalgesia induced by …

Peripheral N-methyl-d-aspartate receptors contribute to mechanical hypersensitivity in a rat model of inflammatory temporomandibular joint pain

JJ Ivanusic, D Beaini, RJ Hatch, V Staikopoulos… - European Journal of …, 2011 - Elsevier
The aim of this study was to determine whether peripheral N-methyl-d-aspartate (NMDA)
receptors are involved in inflammation-induced mechanical hypersensitivity of the …

The P2X7 receptor, cathepsin S and fractalkine in the trigeminal subnucleus caudalis signal persistent hypernociception in temporomandibular rat joints

R Bonfante, MH Napimoga, CG Macedo, HB Abdalla… - Neuroscience, 2018 - Elsevier
Temporomandibular joint (TMJ) is frequently involved with rheumatoid arthritis with a high
prevalence that could result in a chronic pain state. Once the disease is established in the …

Characterization of tachykinin receptors mediating plasma extravasation and vasodilatation in normal and acutely inflamed knee joints of the rat

FY Lam, MCS Wong - British journal of pharmacology, 1996 - Wiley Online Library
1 Inflammatory actions of tachykinins in normal rat knee joints were compared with those of
animals with acutely inflamed joints induced by intra‐articular injection of 2% carrageenan …

[HTML][HTML] Putative antinociceptive action of nitric oxide in the caudal part of the spinal trigeminal nucleus during chronic carrageenan-induced arthritis in the rat …

SA Tesser-Viscaíno, A Denadai-Souza, SA Teixeira… - Brain Research, 2009 - Elsevier
In order to investigate a putative role for nitric oxide (NO) in the central nociceptive
processing following carrageenan-induced arthritis in the rat temporomandibular joint (TMJ) …

Deficient cytokine control modulates temporomandibular joint pain in rheumatoid arthritis

N Ahmed, AI Catrina, AO Alyamani… - European Journal of …, 2015 - Wiley Online Library
The aim was to investigate how endogenous cytokine control of tumor necrosis factor (TNF)
influences temporomandibular joint (TMJ) pain in relation to the role of anti‐citrullinated …

Bradykinin expression in synovial tissues and synovial fluids obtained from patients with internal derangement of the temporomandibular joint

T Suzuki, N Segami, M Nishimura, J Sato, T Nojima - Cranio®, 2003 - Taylor & Francis
Bradykinin has been implicated in the pathogenesis of inflammatory arthritis by virtue of the
potent pro-inflammatory properties. The purpose of this study is to investigate the expression …

Anti‐inflammatory effects of propranolol in the temporomandibular joint of female rats and its contribution to antinociceptive action

FB Zanelatto, EV Dias, JM Teixeira… - … journal of pain, 2018 - Wiley Online Library
Background β‐Blockers reduce temporomandibular joint (TMJ) pain. We asked whether they
also reduce TMJ inflammation and, if so, whether this anti‐inflammatory effect contributes to …

Relationships between pain-related mediators and both synovitis and joint pain in patients with internal derangements and osteoarthritis of the temporomandibular …

M Nishimura, N Segami, K Kaneyama, T Suzuki… - Oral Surgery, Oral …, 2002 - Elsevier
Objective. The purpose of this study was to investigate the correlations between the
concentrations of pain-related mediators in synovial fluid and the degree of synovitis and …

Tachykinin regulation of basal synovial blood flow

WR Ferrell, JC Lockhart… - British journal of …, 1997 - Wiley Online Library
Experiments were performed to investigate the role of endogenously released tachykinins in
the regulation of blood flow to the rat knee joint. Synovial perfusion was assessed by laser …