The 5-hydroxytryptamine (serotonin, 5-HT) is an important inflammatory mediator found in
high levels in the synovial fluid of the temporomandibular joint (TMJ) of patients with …

A considerable amount of evidence suggests that temporomandibular joint (TMJ) pain
associated with temporomandibular disorder results, at least in part, from an inflammatory …

The pathophysiology of chronic inflammatory pain remains poorly understood. In this
context, we developed an experimental model in which successive daily injection of …

Summary Substance P (SP)-, neurokinin A (NKA)-, calcitonin gene-related peptide (CGRP)-
and neuropeptide Y (NPY) qike immunoreactivity (-LI) was studied in rats' cerebrospinal fluid …

Aims: To elucidate the neuronal mechanisms underlying chronic pain of the
temporomandibular joint (TMJ), expression of phosphorylated extracellular signal-regulated …

BACKGROUND AND PURPOSE We investigated the effect of the phosphodiesterase‐5
inhibitor, tadalafil, on the acute hypernociception in rat models of arthritis. EXPERIMENTAL …

Relevance of tumour necrosis factor-α for the inflammatory and nociceptive responses evoked by
carrageenan in the mouse paw - PMC Back to Top Skip to main content NIH NLM Logo Access …

Both pro-nociceptive and antinociceptive mediators are released in the tissues during
inflammation. Balance of these two types of mediators determines the induction and …

Temporomandibular disorder (TMD) is a common painful condition of the
temporomandibular joint (TMJ) and associated structures. Stress is a significant risk factor …

We used an experimental model of neurogenic inflammation, plasma extravasation induced
by bradykinin or capsaicin, to study the effect of receptor-selective opioid agonists on …