[HTML][HTML] Characterization of bronchoalveolar lavage fluid microbiota in acute exacerbations of bronchiectasis with non-tuberculous mycobacterial detection

Q Xu, Z Mei, Q Zha, J Chen, H Qin, B Liu, Z Jie… - International Journal of …, 2024 - Elsevier
Objectives Non-tuberculous mycobacteria (NTM) frequently colonize the airways of patients
with bronchiectasis; however, there has been limited research into airway microbiota …

[HTML][HTML] 1884. Metagenomic Sequencing of the Lung Microbiota Facilitates Diagnosis and Prognosis of Nontuberculous Mycobacterial Pulmonary Disease

Y Chen, Q Miao, B Hu - Open Forum Infectious Diseases, 2023 - ncbi.nlm.nih.gov
Background The incidence of nontuberculous mycobacterial pulmonary disease (PNTM) is
rising, but available diagnostics and treatments have limitations. The lung microbiota plays …

Pathogen metagenomics reveals distinct lung microbiota signatures between bacteriologically confirmed and negative tuberculosis patients

L Ding, Y Liu, X Wu, M Wu, X Luo, H Ouyang… - Frontiers in Cellular …, 2021 - frontiersin.org
Understanding the dynamics of lung microbiota in tuberculosis patients, especially those
who cannot be confirmed bacteriologically in clinical practice, is imperative for accurate …

Association between Clinical Characteristics and Microbiota in Bronchiectasis Patients Based on Metagenomic Next-Generation Sequencing Technology

D Shen, X Lv, H Zhang, C Fei, J Feng, J Zhou… - Polish Journal of …, 2024 - sciendo.com
This study aimed to investigate the disparities between metagenomic next-generation
sequencing (mNGS) and conventional culture results in patients with bronchiectasis …

Deciphering the microbial landscape of lower respiratory tract infections: insights from metagenomics and machine learning

J Li, A Xiong, J Wang, X Wu, L Bai, L Zhang… - Frontiers in Cellular …, 2024 - frontiersin.org
Background Lower respiratory tract infections represent prevalent ailments. Nonetheless,
current comprehension of the microbial ecosystems within the lower respiratory tract …

[HTML][HTML] Changes in the airway microbiome in patients with bronchiectasis

D Lu, C Li, Z Zhong, M Abudouaini, A Amar, H Wu… - Medicine, 2023 - journals.lww.com
This study used metagenomic next-generation sequencing (mNGS) technology to explore
the changes of the microbial characteristics in the lower respiratory tract in patients with …

Different Lung Microbiota Community States are Associated with Pulmonary Nontuberculous Mycobacterial Disease Prognosis

Y Chen, Q Miao, R Bao, H Qu, J Shen, N Li… - Available at SSRN … - papers.ssrn.com
Background: The incidence of nontuberculous mycobacterial pulmonary disease (PNTM) is
rising, but the available treatments have limitations. Currently, the understanding of the …

Insights into the unique lung microbiota profile of pulmonary tuberculosis patients using metagenomic next-generation sequencing

G Xiao, Z Cai, Q Guo, T Ye, Y Tang, P Guan… - Microbiology …, 2022 - Am Soc Microbiol
The microbiota plays an important role in human health and disease development. The lung
microbiota profile in pulmonary tuberculosis (TB) patients and the effects of anti-TB treatment …

[HTML][HTML] Sputum bacterial microbiota signature as a surrogate for predicting disease progression of nontuberculous mycobacterial lung disease

HL Huang, CH Lin, MR Lee, WC Huang… - International Journal of …, 2024 - Elsevier
Objectives Predicting progression of nontuberculous mycobacterial lung disease (NTM-LD)
remains challenging. This study evaluated whether sputum bacterial microbiome diversity …

A novel microbiota stratification system predicts future exacerbations in bronchiectasis

GB Rogers, NMM Zain, KD Bruce, LD Burr… - Annals of the …, 2014 - atsjournals.org
Rationale: Although airway microbiota composition correlates with clinical measures in non–
cystic fibrosis bronchiectasis, these data are unlikely to provide useful prognostic information …