Rapid and Simultaneous Quantification of Five Quinolizidine Alkaloids in Lupinus angustifolius L. and Its Processed Foods by UPLC–MS/MS

IM Hwang, HW Lee, HM Lee, JS Yang, HY Seo… - ACS …, 2020 - ACS Publications
Quinolizidine alkaloids (QAs) are toxic secondary metabolites of Lupinus plants. This study
reports the simultaneous quantification of five alkaloids from Lupinus angustifolius L. and its …

Validation and determination of quinolizidine alkaloids (QAs) in lupin products by gas chromatography with flame ionization detection (GC-FID)

HW Lee, IM Hwang, HM Lee, JS Yang, EJ Park… - Analytical …, 2020 - Taylor & Francis
Products of lupin, a leguminous plant belonging to genus Lupinus, have high protein
contents and are consumed in Mediterranean and Middle East countries. However …

Quantitation of Lupinus spp. Quinolizidine Alkaloids by qNMR and Accelerated Debittering with a Resin-Based Protocol

NA Madelou, E Melliou, P Magiatis - Molecules, 2024 - mdpi.com
Quinolizidine alkaloids (QAs) are toxic secondary metabolites of the Lupinus species, the
presence of which limits the expansion of lupin beans consumption, despite their high …

Determination of quinolizidine alkaloids in different Lupinus species by NACE using UV and MS detection

M Ganzera, A Krüger, M Wink - Journal of Pharmaceutical and Biomedical …, 2010 - Elsevier
Lupin seeds are important for animal and human nutrition. However, they may contain toxic
quinolizidine alkaloids (QA). Analytical methods for a reliable alkaloid determination are …

The fate of quinolizidine alkaloids during the processing of lupins (Lupinus spp.) for human consumption

S Schryvers, C Arinzechukwu, B Miserez, M Eeckhout… - Food Chemistry, 2023 - Elsevier
Lupin, a protein-rich grain legume, and products thereof, are becoming increasingly
important in our diets. However, variable and high concentrations of quinolizidine alkaloids …

Development and validation of a rapid and sensitive LC-MS/MS approach for alkaloid testing in different Lupinus species

T Khedr, A Juhász, KB Singh, R Foley… - Journal of Food …, 2023 - Elsevier
Foods derived from lupin are attracting consumers and producers for their nutritional value
and low cost of production. Lupin products may pose a health risk to consumers due to the …

Quinolizidine alkaloids in lupine flour and lupine products from the German retail market and risk assessment of the results regarding human health

O Keuth, HU Humpf, P Fürst - Food Additives & Contaminants: Part …, 2023 - Taylor & Francis
This study describes the analysis of five quinolizidine alkaloids (QA), ie 13-OH-lupanine,
lupanine, lupinine, angustifoline and sparteine in 30 samples of lupine flours, lupine seeds …

Impact of environmental factors on the presence of quinolizidine alkaloids in lupins: a review

C Rodés-Bachs… - Food Additives & …, 2023 - Taylor & Francis
Lupin seeds have a high potential as an alternative for animal proteins in feed and food.
However, the possible presence of alkaloids hinders the usage of lupins in human diets …

Evaluation of total quinolizidine alkaloids content in lupin flours, lupin‐based ingredients, and foods

D Resta, G Boschin, A D'Agostina… - Molecular nutrition & …, 2008 - Wiley Online Library
Lupin proteins are gaining attention to replace animal proteins and other plants ingredients
in several foods such as bakery products, imitation dairy and meat products, and beverages …

New Analytical Approach to Quinolizidine Alkaloids and Their Assumed Biosynthesis Pathways in Lupin Seeds

D Namdar, PPJ Mulder, E Ben-Simchon, Y Hacham… - Toxins, 2024 - mdpi.com
Alkaloids play an essential role in protecting plants against herbivores. Humans can also
benefit from the pharmacological effects of these compounds. Plants produce an immense …