Neuronal network excitability in Alzheimer's disease: the puzzle of similar versus divergent roles of amyloid β and tau
Alzheimer's disease (AD) is the most frequent neurodegenerative disorder that commonly
causes dementia in the elderly. Recent evidence indicates that network abnormalities …
causes dementia in the elderly. Recent evidence indicates that network abnormalities …
Synaptic depression and aberrant excitatory network activity in Alzheimer's disease: two faces of the same coin?
Neurodegenerative diseases, including Alzheimer's disease (AD), target specific and
functionally connected neuronal networks, raising the possibility that neurodegeneration …
functionally connected neuronal networks, raising the possibility that neurodegeneration …
Circadian and brain state modulation of network hyperexcitability in Alzheimer's disease
R Brown, AD Lam, A Gonzalez-Sulser, A Ying, M Jones… - Eneuro, 2018 - eneuro.org
Network hyperexcitability is a feature of Alzheimer'disease (AD) as well as numerous
transgenic mouse models of AD. While hyperexcitability in AD patients and AD animal …
transgenic mouse models of AD. While hyperexcitability in AD patients and AD animal …
Network excitability dysfunction in Alzheimer's disease: insights from in vitro and in vivo models
Recent reports have drawn attention to dysfunctions of intrinsic neuronal excitability and
network activity in Alzheimer disease (AD). Here we review the possible causes of these …
network activity in Alzheimer disease (AD). Here we review the possible causes of these …
Altered excitatory and inhibitory neuronal subpopulation parameters are distinctly associated with tau and amyloid in Alzheimer's disease
Background: Neuronal-and circuit-level abnormalities of excitation and inhibition are shown
to be associated with tau and amyloid-beta (Aβ) in preclinical models of Alzheimer's disease …
to be associated with tau and amyloid-beta (Aβ) in preclinical models of Alzheimer's disease …
[HTML][HTML] Neuronal hyperexcitability in Alzheimer's disease: what are the drivers behind this aberrant phenotype?
Alzheimer's disease (AD) is a progressive neurodegenerative disorder leading to loss of
cognitive abilities and ultimately, death. With no cure available, limited treatments mostly …
cognitive abilities and ultimately, death. With no cure available, limited treatments mostly …
Neurophysiological signatures in Alzheimer's disease are distinctly associated with TAU, amyloid-β accumulation, and cognitive decline
Neural synchrony is intricately balanced in the normal resting brain but becomes altered in
Alzheimer's disease (AD). To determine the neurophysiological manifestations associated …
Alzheimer's disease (AD). To determine the neurophysiological manifestations associated …
[HTML][HTML] Functional neurophysiological biomarkers of early-stage Alzheimer's disease: A perspective of network hyperexcitability in disease progression
S Tok, A Ahnaou… - Journal of Alzheimer's …, 2022 - content.iospress.com
Network hyperexcitability (NH) has recently been suggested as a potential
neurophysiological indicator of Alzheimer's disease (AD), as new, more accurate biomarkers …
neurophysiological indicator of Alzheimer's disease (AD), as new, more accurate biomarkers …
Unsupervised excitation: GABAergic dysfunctions in Alzheimer's disease
EA Giovannetti, M Fuhrmann - Brain research, 2019 - Elsevier
Alzheimer's disease (AD) is characterized by the classical hallmarks of Aβ-deposition and
tau-pathology that are thought to ultimately lead to synapse and neuron loss. Although long …
tau-pathology that are thought to ultimately lead to synapse and neuron loss. Although long …
[HTML][HTML] Hippocampal oscillatory activity in Alzheimer's disease: toward the identification of early biomarkers?
R Goutagny, S Krantic - Aging and disease, 2013 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) develops for a yet unknown period of time and can progress
undiagnosed for years before its first clinical manifestation consisting of characteristic …
undiagnosed for years before its first clinical manifestation consisting of characteristic …
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