In view of the anticancer activity of thiophene-2, 5-dicar☐ ylic acid, a series of derivatives of
this acid were prepared. Starting from 2, 5-dichloromethylthiophene, thiophene-2, 5 …

Unambiguous synthesis of 2-car☐ y-3-hydroxymethylthiophene, 2-car☐ y-4-
hydroxymethylthiophene and 2-car☐ y-5-hydroxymethylthiophene is reported. From the …

Some 2-(4-substituted phenyl) thiophens and their 3-methyl derivatives have been used to
prepare substituted methylamines, ethylamines, and acetic acids with potential biological …

The reaction of the tetrahydrobenzo [b] thiophene derivatives 1a, b with
benzoylisothiocyanate (2) afforded the thiourea derivatives 3a, b. Cyclization of the latter …

In an analogous reaction with benzoylacetone (Ia-BF; and the sodium salt of the anion in
tetrahydrofuran) ketol Vb, mp 112—114, and thiophene IVb, mp 132~ 133, were obtained in …

The four isomers of thienothiophcne have long been considered only for academic intcrest.
Their usefulness in matcriai science and biology has led lo a renewal of their chcmistry. The …

抄録 Dimethanesulphonylthioalkanes and analogous compounds were synthesized by the
reaction of corresponding sodium thiosulphonate and appropriate dibromide to test the …

Dicyanketendithiolae reacts with equimolar amounts of halogenmethans, substituted with
electron withdrawing groups, to give thiophene-2-thiolates. These compounds are used for …

A great deal of work has been reported in the recent literature on the preparation and
pharmacological evaluation of thiophene compounds. 2-6 Due to the fact that 3-substituted …

Recently, a new route to the bonzo [b]-thiophene series has been described, consisting of
heating cinnamic acids with thionyl chloride and pyridine, which leads to 3-chloro-2-benzo …