Background: Acute myeloid leukemia (AML) is a highly heterogeneous disease
accompanied by the arrest of myeloid cell lineage differentiation due to accumulation of …

BACKGROUND: Acute myeloid leukemia (AML) is characterized by an excess number of
myeloid cells in the marrow with maturation arrest and infiltration of bone marrow (BM) and …

CD200, a protein belonging to the immunoglobulin superfamily, has been associated with a
poor prognosis in lymphoproliferative disorders and in acute leukemia. We studied the …

Aberrant expression of the interleukin-3 receptor alpha chain (IL3RA or CD123) is frequently
observed in patients with a subset of leukemic disorders, including acute myeloid leukemia …

Background: Overexpression of CD200 in ALL patients indicates that it may be useful in the
characterization of leukemia initiating cells (LIC). We aim at investigating the expression …

Acute myeloid leukemia (AML) accounts for approximately 20% of all pediatric acute
leukemias. The outcome of AML is still unsatisfactory. CD123 and CD200 were …

Background: CD34 is a marker of HSCs and haematopoietic progenitor cells as well as a
marker of several other non-haematopoietic cell types. There is much debate on whether …

Abstract C-kit receptor (CD117) and its ligand, stem cell factor, play a key role in normal
hematopoiesis. It has been demonstrated that its expression extremely increases in …

Among other phenotypic markers, CD11b expression has been considered as an
unfavorable prognostic factor, both in terms of overall survival (OS), disease-free survival …

In 141 adult patients with diagnosis of acute myeloid leukemia the overall expression and
intensity of expression of CD34 antigen on leukemic cells was investigated. Myeloid blasts …