Non-vitamin K oral anticoagulants in atrial fibrillation: Where are we now?

MS Dzeshka, GYH Lip - Trends in cardiovascular medicine, 2015 - Elsevier
Atrial fibrillation (AF) confers increased risk of stroke and other thromboembolic events, and
oral anticoagulation therefore is the essential part of AF management to reduce the risk of …

Comparison of anticoagulant therapy for atrial fibrillation-novel oral anticoagulants versus vitamin K antagonists

ST Chen, MR Patel - Progress in Cardiovascular Diseases, 2018 - Elsevier
In patients with non-valvular atrial fibrillation (NVAF), oral anticoagulation is important for
prevention of stroke and systemic embolism (SE). While Vitamin K antagonists (VKAs) have …

Clinical significance of non-vitamin K antagonist oral anticoagulants in the management of atrial fibrillation

G Santarpia, A Curcio, G Sibilio, C Indolfi - Circulation Journal, 2015 - jstage.jst.go.jp
Atrial fibrillation (AF) is the most commonly observed rhythm disorder in clinical practice. It is
associated with a high risk of thromboembolic stroke and increased cardiovascular mortality …

[HTML][HTML] The nonvitamin K antagonist oral anticoagulants and atrial fibrillation: challenges and considerations

A Plitt, S Bansilal - Journal of atrial fibrillation, 2017 - ncbi.nlm.nih.gov
Purpose The nonvitamin K antagonist oral anticoagulants (NOACs) dabigatran, rivaroxaban,
apixaban, and edoxaban are used for the reduction of the risk of stroke or systemic …

Vitamin K antagonists: relative strengths and weaknesses vs. direct oral anticoagulants for stroke prevention in patients with atrial fibrillation

A Zirlik, C Bode - Journal of thrombosis and thrombolysis, 2017 - Springer
Vitamin K antagonists (VKAs) have been the mainstay of anticoagulation therapy for more
than 50 years. VKAs are mainly used for the prevention of stroke in patients with atrial …

Non–vitamin K antagonist oral anticoagulants in the treatment of atrial fibrillation

AC Fanaroff, EM Ohman - Annual review of medicine, 2019 - annualreviews.org
Atrial fibrillation (AF) increases a patient's stroke risk four-to five-fold. Anticoagulation with
the vitamin K antagonist (VKA) warfarin reduces the risk of stroke by 67%, but warfarin …

Comparative efficacy and safety of the non–vitamin K antagonist oral anticoagulants for patients with nonvalvular atrial fibrillation

K Senoo, GYH Lip - Seminars in Thrombosis and Hemostasis, 2015 - thieme-connect.com
The non–vitamin K antagonist oral anticoagulants (NOACs), such as the thrombin inhibitor
(dabigatran) and the direct factor Xa inhibitors (rivaroxaban, apixaban, and edoxaban), have …

New anticoagulation drugs for atrial fibrillation

TS Potpara, GYH Lip - Clinical Pharmacology & Therapeutics, 2011 - Wiley Online Library
Atrial fibrillation (AF) confers an increased risk of ischemic stroke or thromboembolism that is
reduced by long‐term oral anticoagulant therapy. Until recently, the latter has typically been …

Anticoagulant prevention in patients with atrial fibrillation: alternatives to vitamin K antagonists

D Kozlowski, S Budrejko, G Raczak… - Current …, 2013 - ingentaconnect.com
Patients with nonvalvular atrial fibrillation (AF) and risk factors for stroke need
anticoagulation to avoid thromboembolic complications. Vitamin K antagonists (VKAs) are …

Navigating the choice of oral anticoagulation therapy for atrial fibrillation in the NOAC era

D Hammersley, M Signy - Therapeutic advances in chronic …, 2017 - journals.sagepub.com
Atrial fibrillation (AF) is a major cause of ischaemic stroke. The majority of these strokes can
be prevented by treatment with oral anticoagulation therapy. The advent of non-vitamin K …