Clathrin hub expression dissociates the actin‐binding protein Hip1R from coated pits and disrupts their alignment with the actin cytoskeleton

EM Bennett, CY Chen, ÅEY Engqvist‐Goldstein… - Traffic, 2001 - Wiley Online Library
The actin cytoskeleton has been implicated in the maintenance of discrete sites for clathrin‐
coated pit formation during receptor‐mediated endocytosis in mammalian cells, and its …

Regulation of Hip1r by epsin controls the temporal and spatial coupling of actin filaments to clathrin-coated pits

RJ Brady, CK Damer, JE Heuser… - Journal of Cell …, 2010 - journals.biologists.com
Recently, it has become clear that the actin cytoskeleton is involved in clathrin-mediated
endocytosis. During clathrin-mediated endocytosis, clathrin triskelions and adaptor proteins …

The actin-binding protein Hip1R associates with clathrin during early stages of endocytosis and promotes clathrin assembly in vitro

AEY Engqvist-Goldstein, RA Warren… - The Journal of cell …, 2001 - rupress.org
Huntingtin-interacting protein 1 related (Hip1R) is a novel component of clathrin-coated pits
and vesicles and is a mammalian homologue of Sla2p, an actin-binding protein important for …

Actin dynamics counteract membrane tension during clathrin-mediated endocytosis

S Boulant, C Kural, JC Zeeh, F Ubelmann… - Nature cell …, 2011 - nature.com
Clathrin-mediated endocytosis is independent of actin dynamics in many circumstances but
requires actin polymerization in others. We show that membrane tension determines the …

[HTML][HTML] Clathrin-and AP-2-binding sites in HIP1 uncover a general assembly role for endocytic accessory proteins

SK Mishra, NR Agostinelli, TJ Brett, I Mizukami… - Journal of Biological …, 2001 - ASBMB
Clathrin-mediated endocytosis is a major pathway for the internalization of macromolecules
into the cytoplasm of eukaryotic cells. The principle coat components, clathrin and the AP-2 …

[HTML][HTML] A flat BAR protein promotes actin polymerization at the base of clathrin-coated pits

L Almeida-Souza, RAW Frank, J García-Nafría… - Cell, 2018 - cell.com
Multiple proteins act co-operatively in mammalian clathrin-mediated endocytosis (CME) to
generate endocytic vesicles from the plasma membrane. The principles controlling the …

[HTML][HTML] HIP1 and HIP12 display differential binding to F-actin, AP2, and clathrin: Identification of a novel interaction with clathrin light chain

V Legendre-Guillemin, M Metzler… - Journal of Biological …, 2002 - ASBMB
Huntingtin-interacting protein 1 (HIP1) and HIP12 are orthologues of Sla2p, a yeast protein
with essential functions in endocytosis and regulation of the actin cytoskeleton. We now …

Inhibition of clathrin-coated pit assembly by an Eps15 mutant

A Benmerah, M Bayrou… - Journal of cell …, 2000 - journals.biologists.com
Recent data have shown that Eps15, a newly identified component of clathrin-coated pits
constitutively associated with the AP-2 complex, is required for receptor-mediated …

Clathrin light chain directs endocytosis by influencing the binding of the yeast Hip1R homologue, Sla2, to F-actin

DR Boettner, H Friesen, B Andrews… - Molecular biology of the …, 2011 - Am Soc Cell Biol
The role of clathrin light chain (CLC) in clathrin-mediated endocytosis is not completely
understood. Previous studies showed that the CLC N-terminus (CLC-NT) binds the …

[HTML][HTML] An extended interaction site determines binding between AP180 and AP2 in clathrin mediated endocytosis

S Naudi-Fabra, CA Elena-Real, IM Vedel… - Nature …, 2024 - nature.com
The early phases of clathrin mediated endocytosis are organized through a highly complex
interaction network mediated by clathrin associated sorting proteins (CLASPs) that comprise …