Phase II trial of curcumin in patients with advanced pancreatic cancer
N Dhillon, BB Aggarwal, RA Newman, RA Wolff… - Clinical cancer …, 2008 - AACR
Purpose: Pancreatic cancer is almost always lethal, and the only US Food and Drug
Administration–approved therapies for it, gemcitabine and erlotinib, produce objective …
Administration–approved therapies for it, gemcitabine and erlotinib, produce objective …
[HTML][HTML] Therapeutic applications of curcumin for patients with pancreatic cancer
M Kanai - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
A number of preclinical studies have demonstrated anticancer effects for curcumin in various
types of tumors, including pancreatic cancer. Curcumin has anticancer effects both alone …
types of tumors, including pancreatic cancer. Curcumin has anticancer effects both alone …
Curcumin and gemcitabine in patients with advanced pancreatic cancer
R Epelbaum, M Schaffer, B Vizel, V Badmaev… - Nutrition and …, 2010 - Taylor & Francis
Curcumin has a potent antiproliferative activity and can also potentiate the antitumor effect of
gemcitabine. This study was undertaken to evaluate the activity and feasibility of …
gemcitabine. This study was undertaken to evaluate the activity and feasibility of …
[HTML][HTML] Curcumin anticancer studies in pancreatic cancer
S Bimonte, A Barbieri, M Leongito, M Piccirillo… - Nutrients, 2016 - mdpi.com
Pancreatic cancer (PC) is one of the deadliest cancers worldwide. Surgical resection
remains the only curative therapeutic treatment for this disease, although only the minority of …
remains the only curative therapeutic treatment for this disease, although only the minority of …
A phase I/II study of gemcitabine-based chemotherapy plus curcumin for patients with gemcitabine-resistant pancreatic cancer
M Kanai, K Yoshimura, M Asada, A Imaizumi… - Cancer chemotherapy …, 2011 - Springer
Purpose Curcumin, a plant-derived natural polyphenol, could be a promising anti-cancer
drug and shows synergic effects with cytotoxic agents. We evaluated the safety and …
drug and shows synergic effects with cytotoxic agents. We evaluated the safety and …
[PDF][PDF] The dark side of curcumin
E Burgos‐Morón, JM Calderón‐Montaño… - International journal of …, 2010 - Citeseer
Dear Editor, Curcumin is a yellow–orange pigment obtained from the plant Curcuma longa.
The powdered rhizome of this plant, called turmeric, is a common ingredient in curry …
The powdered rhizome of this plant, called turmeric, is a common ingredient in curry …
Curcumin: the story so far
RA Sharma, AJ Gescher, WP Steward - European journal of cancer, 2005 - Elsevier
Curcumin is a polyphenol derived from the herbal remedy and dietary spice turmeric. It
possesses diverse anti-inflammatory and anti-cancer properties following oral or topical …
possesses diverse anti-inflammatory and anti-cancer properties following oral or topical …
Clinical studies with curcumin
CH Hsu, AL Cheng - The molecular targets and therapeutic uses of …, 2007 - Springer
Curcumin has long been expected to be a therapeutic or preventive agent for several major
human diseases because of its antioxidative, anti-inflammatory, and anticancerous effects …
human diseases because of its antioxidative, anti-inflammatory, and anticancerous effects …
[HTML][HTML] Exploring the contribution of curcumin to cancer therapy: A systematic review of randomized controlled trials
C De Waure, C Bertola, G Baccarini, M Chiavarini… - Pharmaceutics, 2023 - mdpi.com
Although the anticancer role of curcumin has been extensively addressed in preclinical
research, only a few studies were carried out in humans, with conflicting results. The aim of …
research, only a few studies were carried out in humans, with conflicting results. The aim of …
Phytosome complex of curcumin as complementary therapy of advanced pancreatic cancer improves safety and efficacy of gemcitabine: Results of a prospective …
D Pastorelli, ASC Fabricio, P Giovanis… - Pharmacological …, 2018 - Elsevier
A large body of biomedical evidence indicates that activation of Nrf2 by curcumin increases
the nucleophilic tone and damps inflammation cumulatively supporting the malignant …
the nucleophilic tone and damps inflammation cumulatively supporting the malignant …