S83 Repeatability and inter-relationships of small airway biomarkers

S Gonem, I Ball, S Corkill, D Desai, A Singapuri… - Thorax, 2011 - thorax.bmj.com
Introduction and objectives There is evidence that the small airways may have an important
role in asthma, and a number of physiological techniques have been developed to assess …

[HTML][HTML] Association between blood eosinophil count and small airway eosinophils in smokers with and without COPD

T Maetani, N Tanabe, A Sato, Y Shiraishi… - ERJ Open …, 2023 - Eur Respiratory Soc
Introduction Airway eosinophilic inflammation is a pathological feature in a subgroup of
patients with COPD and in some smokers with a high COPD risk. Although blood eosinophil …

Are sputum eosinophil cationic protein and eosinophils differently associated with clinical and functional findings of asthma?

S Cianchetti, E Bacci, L Ruocco, T Pavia… - Clinical & …, 2014 - Wiley Online Library
Background Sputum eosinophil counts and eosinophil cationic protein (ECP) levels are
usually increased in asthmatic patients. The correlation between sputum eosinophils or ECP …

Pulmonary function, diffusing capacity, and inflammation in healthy and asthmatic subjects exposed to ultrafine particles

AP Pietropaoli, MW Frampton, RW Hyde… - Inhalation …, 2004 - Taylor & Francis
Particulate air pollution is associated with asthma exacerbations and increased morbidity
and mortality from respiratory causes. Ultrafine particles (particles less than 0.1 μ m in …

Different impacts of blood and sputum eosinophil counts on lung function and clinical outcomes in asthma: findings from the COREA cohort

DD Pham, JH Lee, JY Kim, J An, WJ Song, HS Kwon… - Lung, 2022 - Springer
Abstract Purpose Blood (EOS-B) and sputum (EOS-S) eosinophil counts may contribute
differently to asthma pathogenesis. We compared the impact of the baseline EOS-B and …

Sputum Eosinophil Peroxidase Identifies a Subset of Asthmatics with Severe Airflow Obstruction and Frequent Exacerbations

M Tang, MC Peters, AR Charbit, E Dunican… - … Biomarkers and Uses …, 2022 - atsjournals.org
Conclusions: Sputum EPO is a sensitive measure of airway eosinophilic inflammation, and it
identifies eosinophilic patients who may be misclassified by blood eosinophil measures …

Relationship between small airway function and health status, dyspnea and disease control in asthma

T Takeda, T Oga, A Niimi, H Matsumoto, I Ito… - Respiration, 2010 - karger.com
Background: Small airways play important roles in the pathophysiology of asthma. However,
relationships between small airway involvement and health status and dyspnea have not …

High blood eosinophil counts predict sputum eosinophilia in patients with severe asthma

SJ Fowler, G Tavernier, R Niven - Journal of Allergy and Clinical …, 2015 - jacionline.org
The mechanism for increased bronchomotor tone in obesity is unknown, but several
hypotheses are possible. Obese subjects may have decreased breathing amplitude leading …

Characterization of exhaled breath particles collected by an electret filter technique

ÅD Tinglev, S Ullah, G Ljungkvist… - Journal of breath …, 2016 - iopscience.iop.org
Aerosol particles that are present in exhaled breath carry nonvolatile components and have
gained interest as a specimen for potential biomarkers. Nonvolatile compounds detected in …

[引用][C] Exhaled breath particles—a biomarker for detection of lung disease

K Schwarz, JM Hohlfeld, H Biller, H Windt, W Koch - European Aerosol Conference, 2009