Background: Neovascularization, also known as angiogenesis, is the process of capillary
sprouting from pre-existing blood vessels. This physiological process is a hallmark event in …

It is now well established that angiogenesis is an obligatory event for the growth and
progression of solid tumors beyond the size limit (∼ 2 mm diameter) imposed by simple …

Since early seventies of the twentieth century, through seminal work of Judah Folkman,
angiogenesis, the process of new blood vessel sprouting from the existing vasculature, was …

Deregulated angiogenesis has been identified as a key contributor in a number of
pathological conditions including cancer. It is a complex process, which involves highly …

Angiogenesis is the process through which novel blood vessels are formed from pre-existing
ones and it is involved in both physiological and pathological processes of the body …

Tumor angiogenesis is critically important for the growth of solid tumors as tumors remain in
dormant phase for a long time in the absence of the initiation of blood vessel formation …

Deregulation of angiogenesis–the growth of new blood vessels from an existing vasculature–
is a main driving force in many severe human diseases including cancer. As such, tumor …

Tumor-associated angiogenesis is a key target for anti-cancer therapy. The imbalance
between pro-angiogenic and anti-angiogenic signals elicited by tumor cells or tumor …

Tumour angiogenesis is the formation of new blood vessels to support the growth of a
tumour. This process is critical for tumour progression and metastasis, making it an attractive …

Chemotherapeutic agents do not specifically target tumor cells, but rather interfere with cell
division or inhibit enzymes involved DNA replication or metabolism. These drugs therefore …