Frequency, severity, and prediction of tuberculous meningitis immune reconstitution inflammatory syndrome

S Marais, G Meintjes, DJ Pepper… - Clinical infectious …, 2013 - academic.oup.com
Background. Tuberculosis immune reconstitution inflammatory syndrome (IRIS) is a
common cause of deterioration in human immunodeficiency virus (HIV)–infected patients …

Neutrophil-associated central nervous system inflammation in tuberculous meningitis immune reconstitution inflammatory syndrome

S Marais, KA Wilkinson, M Lesosky… - Clinical infectious …, 2014 - academic.oup.com
Background. The immunopathogenesis of tuberculosis-associated immune reconstitution
inflammatory syndrome (IRIS) remains incompletely understood, and we know of only 1 …

[HTML][HTML] HIV-1 tuberculosis-associated immune reconstitution inflammatory syndrome

RPJ Lai, G Meintjes, RJ Wilkinson - Seminars in immunopathology, 2016 - Springer
Patients co-infected with HIV-1 and tuberculosis (TB) are at risk of developing TB-associated
immune reconstitution inflammatory syndrome (TB-IRIS) following commencement of …

Paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome after early initiation of antiretroviral therapy in a randomized clinical trial

D Laureillard, O Marcy, Y Madec, S Chea, S Chan… - Aids, 2013 - journals.lww.com
Objective: To analyze cases of paradoxical tuberculosis-associated immune reconstitution
inflammatory syndrome (TB-IRIS) in the CAMbodian Early versus Late Introduction of …

Immune reconstitution inflammatory syndrome of tuberculosis among HIV-infected patients receiving antituberculous and antiretroviral therapy

W Manosuthi, S Kiertiburanakul, T Phoorisri… - Journal of Infection, 2006 - Elsevier
OBJECTIVE: To determine the frequency, risk factors and mortality rate of immune
reconstitution inflammatory syndrome (IRIS) of tuberculosis (TB) in patients co-infected with …

Neurologic manifestations of paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome: a case series

DJ Pepper, S Marais, G Maartens… - Clinical Infectious …, 2009 - academic.oup.com
Background. Paradoxical neurologic tuberculosis-associated immune reconstitution
inflammatory syndrome (TB-IRIS) is a potentially life-threatening condition that occurs within …

Corticosteroid-modulated immune activation in the tuberculosis immune reconstitution inflammatory syndrome

G Meintjes, KH Skolimowska, KA Wilkinson… - American journal of …, 2012 - atsjournals.org
Rationale: HIV–tuberculosis-associated immune reconstitution inflammatory syndrome (TB-
IRIS) is an immunopathological reaction to mycobacterial antigens induced by antiretroviral …

[HTML][HTML] The tuberculosis-associated immune reconstitution inflammatory syndrome: recent advances in clinical and pathogenesis research

NF Walker, C Stek, S Wasserman… - Current Opinion in …, 2018 - journals.lww.com
Specific biomarkers would aid in identifying high-risk patients for interventions and a
diagnostic test is needed. Clinicians should consider prednisone for TB-IRIS prevention in …

Inflammasome activation underlying central nervous system deterioration in HIV-associated tuberculosis

S Marais, RPJ Lai, KA Wilkinson… - The Journal of …, 2017 - academic.oup.com
Tuberculous meningitis (TBM) is a frequent cause of meningitis in individuals with human
immunodeficiency virus (HIV) infection, resulting in death in approximately 40% of affected …

Tuberculosis immune reconstitution inflammatory syndrome in countries with limited resources

R Colebunders, L John, V Huyst… - … of Tuberculosis and …, 2006 - ingentaconnect.com
Mycobacterium tuberculosis infection accounts for probably one third of human
immunodeficiency virus (HIV) related immune reconstitution inflammatory syndrome (IRIS) …