Mast cells and immunoglobulin E (IgE) antibodies are thought to promote health by
contributing to host responses to certain parasites, but other beneficial functions have …

Mast cells and IgE are so inextricably linked to the pathology of allergic disorders, including
fatal anaphylaxis, that it can be difficult to think of them in other contexts. Surely, we do not …

Physicians think of mast cells and IgE primarily in the context of allergic disorders, including
fatal anaphylaxis. This 'bad side'of mast cells and IgE is so well accepted that it can be …

IgE-dependent mast cell activation is a major effector mechanism underlying the pathology
associated with allergic disorders. The most dramatic of these IgE-associated disorders is …

Highlights•Mast cell activation can contribute to innate immunity to multiple animal
venoms.•Mast cell granule-associated proteases can degrade toxic components of …

Background In contrast to their clearly defined roles in allergic diseases, the physiologic
functions of Immunoglobulin E antibodies (IgEs) and mast cells (MCs) remain enigmatic …

abstract Physicians think of mast cells and IgE primarily in the context of allergic disorders,
including fatal anaphylaxis. This 'bad side'of mast cells and IgE is so well accepted that it …

The contribution of mast cells in anaphylactic responses to insect venom may be
heterogeneous. On the one hand, activation of mast cells contributes to the pathology by the …

Mast cell degranulation is important in the pathogenesis of anaphylaxis and allergic
disorders. Many animal venoms contain components that can induce mast cell …

Snake bites and bee stings: the mast cell strikes back | Nature Medicine Skip to main content
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