Oltipraz prevents high glucose‐induced oxidative stress and apoptosis in RSC96 Cells through the Nrf2/NQO1 signalling pathway

Z Jiang, M Bian, J Wu, D Li, L Ding… - BioMed Research …, 2020 - Wiley Online Library
Diabetic peripheral neuropathy (DPN) is a common complication of diabetes mellitus (DM).
Schwann cell (SC) apoptosis contributes to the occurrence and development of DPN …

Loganin attenuates high glucose-induced schwann cells pyroptosis by inhibiting ROS generation and NLRP3 inflammasome activation

YC Cheng, LW Chu, JY Chen, SL Hsieh, YC Chang… - Cells, 2020 - mdpi.com
Diabetic peripheral neuropathy (DPN) is caused by hyperglycemia, which induces oxidative
stress and inflammatory responses that damage nerve tissue. Excessive generation of …

Tangluoning, a traditional Chinese medicine, attenuates in vivo and in vitro diabetic peripheral neuropathy through modulation of PERK/Nrf2 pathway

X Yang, W Yao, H Liu, Y Gao, R Liu, L Xu - Scientific reports, 2017 - nature.com
Prolonged hyperglycemia-induced oxidative stress and endoplasmic reticulum stress have
been demonstrated to play a key role in progression of diabetic peripheral neuropathy …

Schwann cells apoptosis is induced by high glucose in diabetic peripheral neuropathy

Y Liu, S Shao, H Guo - Life sciences, 2020 - Elsevier
Diabetic peripheral neuropathy (DPN) is a common complication of diabetes mellitus that
affects approximately half of patients with diabetes. Current treatment regimens cannot treat …

Artesunate inhibits apoptosis and promotes survival in schwann cells via the PI3K/AKT/mTOR axis in diabetic peripheral neuropathy

X Zhang, Z Liang, Y Zhou, F Wang, S Wei… - Biological and …, 2023 - jstage.jst.go.jp
Diabetic peripheral neuropathy (DPN) is an early developing complication of diabetes
mellitus associated with nerve dysfunction. Artesunate (ART), a natural compound extracted …

Tang‐Luo‐Ning, a traditional Chinese medicine, inhibits endoplasmic reticulum stress‐induced apoptosis of Schwann cells under high glucose environment

W Yao, X Yang, J Zhu, B Gao, R Liu… - … and Alternative Medicine, 2017 - Wiley Online Library
Tang‐Luo‐Ning (TLN) has a definite effect in the clinical treatment of diabetic peripheral
neuropathy (DPN). Schwann cells (SCs) apoptosis induced by endoplasmic reticulum stress …

[PDF][PDF] Oxidative stress in diabetic neuropathy: source of reactive oxygen species

M Chopra, K Kaul, J Tarr, R Choudhury… - Endocrinology …, 2012 - researchgate.net
Diabetic neuropathy is a common diabetic complication. Oxidative stress (OS) is a significant
mediator in the development of diabetic neuropathy. Exposing neurons to hyperglycaemia …

Honokiol attenuates high glucose‐induced peripheral neuropathy via inhibiting ferroptosis and activating AMPK/SIRT1/PGC‐1α pathway in Schwann cells

M Hu, W Jiang, C Ye, T Hu, Q Yu, M Meng… - Phytotherapy …, 2023 - Wiley Online Library
Schwann cells injury induced by high glucose (HG) contributes to the development of
diabetic peripheral neuropathy (DPN). Honokiol has been reported to regulate glucose …

Nrf2 and NF-κB modulation by sulforaphane counteracts multiple manifestations of diabetic neuropathy in rats and high glucose-induced changes

G Negi, A Kumar, SS Sharma - Current neurovascular …, 2011 - ingentaconnect.com
High glucose driven reactive oxygen intermediates production and inflammatory damage
are recognized contributors of nerve dysfunction and subsequent damage in diabetic …

Ameliorative potential of rutin in combination with nimesulide in STZ model of diabetic neuropathy: targeting Nrf2/HO-1/NF-kB and COX signalling pathway

R Mittal, A Kumar, DP Singh, M Bishnoi, TC Nag - Inflammopharmacology, 2018 - Springer
Emerging role of Nrf-2/HO-1 in pathogenesis of diabetic neuropathy has been suggested.
Diabetic neuropathy is one of the most common complications of diabetes and more than …