[HTML][HTML] Excess body weight: Novel insights into its roles in obesity comorbidities

X Zhang, S Ha, HCH Lau, J Yu - Seminars in cancer biology, 2023 - Elsevier
Excess body weight is a global health problem due to sedentary lifestyle and unhealthy diet,
affecting 2 billion population worldwide. Obesity is a major risk factor for metabolic diseases …

The obesity paradox in cancer—moving beyond BMI

S Strulov Shachar, GR Williams - Cancer Epidemiology, Biomarkers & …, 2017 - AACR
Body mass index (BMI) and simple counts of weight are easy and available tools in the clinic
and in research. Recent studies have shown that cancer patients with a low normal BMI (or …

The obesity paradox in cancer: epidemiologic insights and perspectives

DH Lee, EL Giovannucci - Current nutrition reports, 2019 - Springer
Abstract Purpose of Review Controversy exists whether excess body fatness (measured by
body mass index (BMI)) is associated with better cancer survival (“obesity paradox”). Here …

[HTML][HTML] Body fatness associations with cancer: evidence from recent epidemiological studies and future directions

SC Larsson, N Spyrou, CS Mantzoros - Metabolism, 2022 - Elsevier
This narrative review highlights current evidence linking greater body fatness to risk of
various cancers, with focus on evidence from recent large cohort studies and pooled …

Global patterns in excess body weight and the associated cancer burden

H Sung, RL Siegel, LA Torre… - CA: a cancer journal …, 2019 - Wiley Online Library
The prevalence of excess body weight and the associated cancer burden have been rising
over the past several decades globally. Between 1975 and 2016, the prevalence of excess …

[HTML][HTML] Molecular mechanisms of western diet-induced obesity and obesity-related carcinogenesis—A narrative review

D Lathigara, D Kaushal, RB Wilson - Metabolites, 2023 - mdpi.com
The present study aims to provide a narrative review of the molecular mechanisms of
Western diet-induced obesity and obesity-related carcinogenesis. A literature search of the …

Obesity and cancer risk: Emerging biological mechanisms and perspectives

KI Avgerinos, N Spyrou, CS Mantzoros, M Dalamaga - Metabolism, 2019 - Elsevier
Continuously rising trends in obesity-related malignancies render this disease spectrum a
public health priority. Worldwide, the burden of cancer attributable to obesity, expressed as …

[HTML][HTML] Mechanisms linking excess adiposity and carcinogenesis promotion

AI Pérez-Hernández, V Catalán… - Frontiers in …, 2014 - frontiersin.org
Obesity constitutes one of the most important metabolic diseases being associated to insulin
resistance development and increased cardiovascular risk. Association between obesity …

The obesity paradox in cancer: clinical insights and perspectives

I Trestini, L Carbognin, C Bonaiuto, G Tortora… - Eating and Weight …, 2018 - Springer
A series of evidence demonstrated that obesity represents an established risk factor for an
increase in the incidence of multiple cancer types and for poor cancer survival …

Obesity as a major risk factor for cancer

G De Pergola, F Silvestris - Journal of obesity, 2013 - Wiley Online Library
The number of cancer cases caused by being obese is estimated to be 20% with the
increased risk of malignancies being influenced by diet, weight change, and body fat …