Recent genome-wide association studies have identified single nucleotide polymorphisms
(SNPs) associated with non-syndromic cleft lip with or without cleft palate (NSCL/P), and …

Objectives: Orofacial clefting is one of the most prevalent craniofacial malformations.
Previous research has demonstrated that unaffected relatives of patients with non-syndromic …

There is increasing evidence that genetic risk variants for non-syndromic cleft lip/palate
(nsCL/P) are also associated with normal-range variation in facial morphology. However …

Family relatives of children with nonsyndromic cleft lip with or without cleft palate (NSCL/P)
who presumably carry a genetic risk yet do not manifest overt oral clefts, often present with …

Historically, craniofacial genetic research has understandably focused on identifying the
causes of craniofacial anomalies and it has only been within the last 10 years, that there has …

Inter-individual variation in facial shape is one of the most noticeable phenotypes in
humans, and it is clearly under genetic regulation; however, almost nothing is known about …

Objective The purpose of this study was to evaluate the transverse craniofacial form in
families with nonsyndromic cleft lip and palate (NSCLP). It was hypothesized that affected as …

We conducted a genome-wide association study for nonsyndromic cleft lip with or without
cleft palate (NSCL/P) in 401 affected individuals and 1,323 controls, with replication in an …

Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is the most common craniofacial
birth defect in humans, affecting 1 in 700 live births. This malformation has a complex …

Several studies have now shown evidence of association between common genetic variants
and quantitative facial traits in humans. The reported associations generally involve simple …