Ischemia/reperfusion injury to the developing brain is a major cause of neurologic
abnormalities in preterm infants. To investigate the underlying mechanisms, we modified a …

Brain injury in the premature infant is an extremely important problem, in part because of the
large absolute number of infants affected yearly. The two principle brain lesions that underlie …

Periventricular leukomalacia (PVL), the principal form of brain injury in the premature infant,
is characterized by overt focal necrotic lesions in periventricular white matter and less …

Hypoxic–ischemic brain injury in premature infants results in cerebral white matter lesions
with prominent oligodendroglial injury and loss, a disorder termed periventricular …

Periventricular white matter injury, the principal variety of brain injury of the human
premature infant, involves differentiating oligodendroglia. Nothing is known of the …

Selective patterns of cerebral injury are observed after a variety of insults at different ages
during development. Distinct populations of cells demonstrate selective vulnerability during …

Neonatal periventricular white matter injury is a major contributor to chronic neurologic
dysfunction. In a neonatal rat stroke model, myelin basic protein (MBP) immunostaining …

Periventricular white matter injury, specifically cystic periventricular leukomalacia (PVL) and
ipsilateral hemorrhage into white matter associated with periventricular-intraventricular …

Oligodendrocytes are the primary cells injured in periventricular leukomalacia (PVL), a
predominant form of brain white matter lesion in preterm infants. To explore the possible …

Damage to the white matter in the brain during development can lead to cerebral palsy (CP),
a heterogeneous group of clinical syndromes that results in life‐long disorders of movement …