The mammalian ovary is a large source of oocytes organized into follicles at various stages
of folliculogenesis. However, only a limited number of them can be used for in vitro embryo …

Abstract Growth Differentiation Factor 8 (GDF8) is a member of the transforming growth
factor-β (TGF-β) family and has been identified as a strong physiological regulator. This …

The last 5–10 years of research in ovarian and oocyte biology has delivered some major
new advances in knowledge of the molecular and cellular processes regulating oocyte …

Purpose To visualize and analyze follicle development in ovarian tissue culture using
physiological concentrations of follicle-stimulating hormone (FSH) and luteinizing hormone …

In vitro follicle development (IVFD) is an adequate model to obtain basic knowledge of
folliculogenesis and provides a tool for ovarian toxicity screening. IVFD yielding competent …

Egg quality dictates fertility outcomes, and although there is a well-documented decline with
advanced reproductive age, how it changes during puberty is less understood. Such …

Women with cancer and low ovarian reserves face serious challenges in infertility treatment.
Ovarian tissue cryopreservation is currently used for such patients to preserve fertility. One …

In mouse ovaries, growth differentiation factor-9 (GDF9) is an oocyte-derived growth factor
that plays an essential role during early follicular development. However, the role of GDF9 …

STUDY QUESTION Which substances and signal transduction pathways are potentially
active downstream to the effect of FSH and LH in the regulation of human oocyte maturation …

Purpose The IGF signaling cascade exerts important regulatory functions in human ovarian
folliculogenesis. The scope of this study was to evaluate the transcription profile of insulin …