The effects of sex, estrous cycle, and social contact on cocaine and heroin self-administration in rats
RT Lacy, JC Strickland, MA Feinstein, AM Robinson… - …, 2016 - Springer
Rationale Preclinical studies indicate that gonadal hormones are important determinants of
drug self-administration. To date, little is known about the influence of sex and estrous cycle …
drug self-administration. To date, little is known about the influence of sex and estrous cycle …
The role of neuroadaptations in relapse to drug seeking
One of the most difficult problems in treating addiction is not withdrawing addicts from drugs,
but preventing relapse. Persistent neuroadaptations are thought to underlie aspects of …
but preventing relapse. Persistent neuroadaptations are thought to underlie aspects of …
[HTML][HTML] Sex-specific mechanism of social hierarchy in mice
WE Van Den Berg, S Lamballais… - …, 2015 - nature.com
The establishment of social hierarchies is a naturally occurring, evolutionarily conserved
phenomenon with a well-established impact on fitness and health. Investigations of complex …
phenomenon with a well-established impact on fitness and health. Investigations of complex …
The neurobiology of social play and its rewarding value in rats
LJMJ Vanderschuren, EJM Achterberg… - … & Biobehavioral Reviews, 2016 - Elsevier
In the young of many mammalian species, including humans, a vigorous and highly
rewarding social activity is abundantly expressed, known as social play behaviour. Social …
rewarding social activity is abundantly expressed, known as social play behaviour. Social …
A cellular mechanism of reward-related learning
JNJ Reynolds, BI Hyland, JR Wickens - Nature, 2001 - nature.com
Positive reinforcement helps to control the acquisition of learned behaviours. Here we report
a cellular mechanism in the brain that may underlie the behavioural effects of positive …
a cellular mechanism in the brain that may underlie the behavioural effects of positive …
Modeling the development of drug addiction in male and female animals
WJ Lynch - Pharmacology Biochemistry and Behavior, 2018 - Elsevier
An increasing emphasis has been placed on the development and use of animal models of
addiction that capture defining features of human drug addiction, including escalation/binge …
addiction that capture defining features of human drug addiction, including escalation/binge …
Social learning and addiction
MA Smith - Behavioural Brain Research, 2021 - Elsevier
Social learning theory, as originally proposed by Albert Bandura, followed 2000 years of
intellectual inquiry into the determinants of human behavior. Reciprocal determinism is a …
intellectual inquiry into the determinants of human behavior. Reciprocal determinism is a …
Improving translation of animal models of addiction and relapse by reverse translation
Critical features of human addiction are increasingly being incorporated into complementary
animal models, including escalation of drug intake, punished drug seeking and taking …
animal models, including escalation of drug intake, punished drug seeking and taking …
Substance-specific environmental influences on drug use and drug preference in animals and humans
A Badiani - Current opinion in neurobiology, 2013 - Elsevier
Highlights•Substance-specificity in drug abuse is determined by environmental influences
unique to the individual.•Central and peripheral drug effects undergo emotional appraisal as …
unique to the individual.•Central and peripheral drug effects undergo emotional appraisal as …
Diazepam promotes choice of abstinence in cocaine self‐administering rats
E Augier, C Vouillac, SH Ahmed - Addiction biology, 2012 - Wiley Online Library
When facing a choice between cocaine and a potent, albeit inessential, non‐drug alternative
(ie water sweetened with saccharin), most cocaine self‐administering rats abstain from …
(ie water sweetened with saccharin), most cocaine self‐administering rats abstain from …