Human embryonic stem (hES) cells can differentiate in vitro, forming embryoid bodies (EBs)
composed of derivatives of all three embryonic germ layers. Spontaneously contracting …

Human embryonic stem cell‐derived cardiomyocytes (hES‐CMs) are thought to recapitulate
the embryonic development of heart cells. Given the exciting potential of hES‐CMs as …

The study of human cardiac tissue development is hampered by the lack of a suitable in vitro
model. We describe the phenotypic properties of cardiomyocytes derived from human …

Background: Embryonic stem cells provide the most promising tool for cell replacement
therapy including transplantation of human embryonic stem (hES) cell-derived …

Human embryonic stem cells have emerged as the prototypical source from which
cardiomyocytes can be derived for use in drug discovery and cell therapy. However, such …

Background—Human embryonic stem cells (hESCs) can be efficiently and reproducibly
directed into cardiomyocytes (CMs) using stage-specific induction protocols. However, their …

Human embryonic stem cells (hESCs) can be coaxed to differentiate Into specific cell types,
including cardiomyocyte-like cells. These cells express cardiac-specific markers and display …

Background—Cardiomyocytes derived from human embryonic stem (hES) cells could be
useful in restoring heart function after myocardial infarction or in heart failure. Here, we …

Cardiomyocytes derived from human embryonic stem cells constitute a promising cell
source for the regeneration of damaged hearts. The assessment of their in vitro functional …

While human embryonic stem cells (hESCs) can differentiate into functional cardiomyocytes,
their immature phenotypes limit their therapeutic application for myocardial regeneration …