The regulatory function of eosinophils

T Wen, ME Rothenberg - Microbiology spectrum, 2016 - Am Soc Microbiol
Eosinophils are a minority circulating granulocyte classically viewed as being involved in
host defense against parasites and promoting allergic reactions. However, a series of new …

Eosinophils: changing perspectives in health and disease

HF Rosenberg, KD Dyer, PS Foster - Nature Reviews Immunology, 2013 - nature.com
Eosinophils have been traditionally perceived as terminally differentiated cytotoxic effector
cells. Recent studies have profoundly altered this simplistic view of eosinophils and their …

A player and coordinator: the versatile roles of eosinophils in the immune system

H Long, W Liao, L Wang, Q Lu - Transfusion Medicine and …, 2016 - karger.com
Eosinophils have traditionally been associated with allergic diseases and parasite infection.
Research advances in the recent decades have brought evolutionary changes in our …

Functions of tissue-resident eosinophils

PF Weller, LA Spencer - Nature Reviews Immunology, 2017 - nature.com
Eosinophils are a prominent cell type in particular host responses such as the response to
helminth infection and allergic disease. Their effector functions have been attributed to their …

Eosinophils: multifaceted biological properties and roles in health and disease

H Kita - Immunological reviews, 2011 - Wiley Online Library
Eosinophils are leukocytes resident in mucosal tissues. During T‐helper 2 (Th2)‐type
inflammation, eosinophils are recruited from bone marrow and blood to the sites of immune …

Eosinophils in innate immunity: an evolving story

R Shamri, JJ Xenakis, LA Spencer - Cell and tissue research, 2011 - Springer
Eosinophils are innate immune leukocytes found in relatively low numbers within the blood.
Terminal effector functions of eosinophils, deriving from their capacity to release their …

The eosinophil

ME Rothenberg, SP Hogan - Annu. Rev. Immunol., 2006 - annualreviews.org
Eosinophils have been considered end-stage cells involved in host protection against
parasites. However, numerous lines of evidence have now changed this perspective by …

Contributions of eosinophils to human health and disease

AD Klion, SJ Ackerman… - Annual Review of …, 2020 - annualreviews.org
The human eosinophil has long been thought to favorably influence innate mucosal
immunity but at times has also been incriminated in disease pathophysiology. Research into …

The regulatory role of eosinophils in viral, bacterial, and fungal infections

P Gaur, I Zaffran, T George… - Clinical and …, 2022 - academic.oup.com
Eosinophils are innate immune cells typically associated with allergic and parasitic
diseases. However, in recent years, eosinophils have also been ascribed a role in keeping …

Biology of the eosinophil

C Blanchard, ME Rothenberg - Advances in immunology, 2009 - Elsevier
In this review, we aim to put in perspective the biology of a multifunctional leukocyte, the
eosinophil, by placing it in the context of innate and adaptive immune responses …