Adenosine A2A receptor antagonists have been proposed as an effective therapy in the
treatment of Parkinson's disease. To explore the possibility that dopamine denervation may …

Brain adenosine A2A receptors have recently attracted considerable attention because of
their interaction with the dopaminergic system and as potential targets for Parkinson's …

The expression of the human adenosine A2A receptor was examined by reverse
transcription polymerase chain reaction in post-mortem human brain tissue that was …

The objective of the work was to study, by in vivo microdialysis, the effect of the adenosine
A2A receptor antagonist 7-(2-phenylethyl)-5-amino-2-(2-furyl)-pyrazolo-[4, 3-e]-1, 2, 4 …

Adenosine has been shown to inhibit dopamine release from striatal slices and
synaptosomes. Recently, a direct interaction between the adenosine A2 receptor and …

To clarify differences in the operating mechanisms of adenosine receptor subtypes (A1 and
A2), striatal extracellular dopamine levels under various conditions were determined by in …

From behavioural and biochemical experiments, we have found evidence for the existence
of a specific adenosine A2a receptor/dopamine D2 receptor interaction in the brain …

Adenosine A2A receptors are abundant in the caudate‐putamen and involved in the motor
control in several species. In MPTP‐treated monkeys, A2A receptor‐blockade with an …

Evidence for a role of dopaminergic neurotransmission in the motor effects of adenosine
antagonists, such as caffeine, is reviewed, based on the existence of specific antagonistic …

Evidence for a role of dopaminergic neurotransmission in the motor effects of adenosine
antagonists, such as caffeine, is reviewed, based on the existence of specific antagonistic …