Phase II clinical trial of curcumin in patients with advanced pancreatic cancer

N Dhillon, RA Wolff, JL Abbruzzese… - Journal of Clinical …, 2006 - ascopubs.org
14151 Background: Pancreatic cancer is virtually always lethal, and the only FDA-approved
therapies-gemcitabine and erlotinib-produce objective responses in less than 10% of …

Curcumin and pancreatic cancer: phase II clinical trial experience

N Dhillon, BB Aggarwal, RA Newman… - Journal of Clinical …, 2007 - ascopubs.org
4599 Background: Pancreatic cancer is virtually always lethal, and the only FDA-approved
therapies–gemcitabine and erlotinib–produce objective responses in less than 10% of …

Phase II trial of curcumin in patients with advanced pancreatic cancer

N Dhillon, BB Aggarwal, RA Newman, RA Wolff… - Clinical cancer …, 2008 - AACR
Purpose: Pancreatic cancer is almost always lethal, and the only US Food and Drug
Administration–approved therapies for it, gemcitabine and erlotinib, produce objective …

Phase II study of curcumin and gemcitabine in patients with advanced pancreatic cancer

R Epelbaum, B Vizel, G Bar-Sela - Journal of Clinical Oncology, 2008 - ascopubs.org
15619 Background: The anti-metabolite gemcitabine is the standard chemotherapy for
advanced pancreatic cancer. Yet, it produces an objective response in less than 10% of …

[HTML][HTML] Therapeutic applications of curcumin for patients with pancreatic cancer

M Kanai - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
A number of preclinical studies have demonstrated anticancer effects for curcumin in various
types of tumors, including pancreatic cancer. Curcumin has anticancer effects both alone …

Curcumin and gemcitabine in patients with advanced pancreatic cancer

R Epelbaum, M Schaffer, B Vizel, V Badmaev… - Nutrition and …, 2010 - Taylor & Francis
Curcumin has a potent antiproliferative activity and can also potentiate the antitumor effect of
gemcitabine. This study was undertaken to evaluate the activity and feasibility of …

Curcumin anticancer studies in pancreatic cancer

S Bimonte, A Barbieri, M Leongito, M Piccirillo… - Nutrients, 2016 - mdpi.com
Pancreatic cancer (PC) is one of the deadliest cancers worldwide. Surgical resection
remains the only curative therapeutic treatment for this disease, although only the minority of …

A phase I/II study of gemcitabine-based chemotherapy plus curcumin for patients with gemcitabine-resistant pancreatic cancer

M Kanai, K Yoshimura, M Asada, A Imaizumi… - Cancer chemotherapy …, 2011 - Springer
Purpose Curcumin, a plant-derived natural polyphenol, could be a promising anti-cancer
drug and shows synergic effects with cytotoxic agents. We evaluated the safety and …

[PDF][PDF] Curcumin and pancreatic cancer: a research and clinical update

CJD Osterman, NR Wall - J Nat Sci, 2015 - researchgate.net
Pancreatic cancer is one of the most devastating types of cancer. The American Cancer
Society has estimated that 48,960 individuals will be diagnosed with pancreatic cancer in …

Therapeutic potential of curcumin in treatment of pancreatic cancer: current status and future perspectives

M Hosseini, SM Hassanian… - Journal of cellular …, 2017 - Wiley Online Library
Pancreatic cancer is among the leading cause of deaths due to cancer with extremely poor
prognosis. Gemcitabine is being used in the treatment of patient with pancreatic ductal …