Structural basis for the broad, antibody-mediated neutralization of H5N1 influenza virus
Q Lin, T Li, Y Chen, SY Lau, M Wei, Y Zhang… - Journal of …, 2018 - Am Soc Microbiol
Human infection with highly pathogenic avian influenza A viruses causes severe disease
and fatalities. We previously identified a potent and broadly neutralizing antibody (bnAb) …
and fatalities. We previously identified a potent and broadly neutralizing antibody (bnAb) …
Epitope mapping of the 2009 pandemic and the A/Brisbane/59/2007 seasonal (H1N1) influenza virus haemagglutinins using mAbs and escape mutants
M Retamal, Y Abed, J Corbeil… - Journal of General …, 2014 - microbiologyresearch.org
mAbs constitute an important biological tool for influenza virus haemagglutinin (HA) epitope
mapping through the generation of escape mutants, which could provide insights into …
mapping through the generation of escape mutants, which could provide insights into …
[HTML][HTML] Pandemic H1N1 influenza infection and vaccination in humans induces cross-protective antibodies that target the hemagglutinin stem
CA Thomson, Y Wang, L Jackson, M Olson… - Frontiers in …, 2012 - frontiersin.org
Most monoclonal antibodies (mAbs) generated from humans infected or vaccinated with the
2009 pandemic H1N1 (pdmH1N1) influenza virus targeted the hemagglutinin (HA) stem …
2009 pandemic H1N1 (pdmH1N1) influenza virus targeted the hemagglutinin (HA) stem …
Neutralizing anti-influenza virus monoclonal antibodies: therapeutics and tools for discovery
O Martinez, T Tsibane, CF Basler - International reviews of …, 2009 - Taylor & Francis
The human antibody response to influenza virus infection plays a protective role against re-
infection, yet little molecular detail is available regarding how human antibodies, when …
infection, yet little molecular detail is available regarding how human antibodies, when …
Broadly neutralizing antibodies against influenza viruses
NS Laursen, IA Wilson - Antiviral research, 2013 - Elsevier
Despite available antivirals and vaccines, influenza continues to be a major cause of
mortality worldwide. Vaccination generally induces an effective, but strain-specific antibody …
mortality worldwide. Vaccination generally induces an effective, but strain-specific antibody …
Broadly neutralizing anti-influenza virus antibodies: enhancement of neutralizing potency in polyclonal mixtures and IgA backbones
W He, CE Mullarkey, JA Duty, TM Moran… - Journal of …, 2015 - Am Soc Microbiol
Current influenza virus vaccines rely upon the accurate prediction of circulating virus strains
months in advance of the actual influenza season in order to allow time for vaccine …
months in advance of the actual influenza season in order to allow time for vaccine …
Hemagglutinin stalk-based monoclonal antibody elicits broadly reactivity against group 1 influenza A virus
J Huang, N Huang, M Fan, L Zhao, Y Luo, P Ding… - Virology Journal, 2020 - Springer
Background Influenza virus remains a continuous and severe threat to public health
worldwide, and its prevention and treatment have always been a major international issue …
worldwide, and its prevention and treatment have always been a major international issue …
Human antibodies reveal a protective epitope that is highly conserved among human and nonhuman influenza A viruses
AG Grandea III, OA Olsen, TC Cox… - Proceedings of the …, 2010 - National Acad Sciences
Influenza remains a serious public health threat throughout the world. Vaccines and
antivirals are available that can provide protection from infection. However, new viral strains …
antivirals are available that can provide protection from infection. However, new viral strains …
A fully human monoclonal antibody possesses antibody‐dependent cellular cytotoxicity (ADCC) activity against the H1 subtype of influenza A virus by targeting a …
The DiversitabTM system produces target specific high titer fully human polyclonal IgG
immunoglobulins from transchromosomic (Tc) bovines shown to be safe and effective …
immunoglobulins from transchromosomic (Tc) bovines shown to be safe and effective …
Intranasal delivery of an IgA monoclonal antibody effective against sublethal H5N1 influenza virus infection in mice
J Ye, H Shao, D Hickman, M Angel, K Xu… - Clinical and Vaccine …, 2010 - Am Soc Microbiol
Highly pathogenic avian H5N1 influenza viruses are endemic in poultry in Asia and pose a
pandemic threat to humans. Since the deployment of vaccines against a pandemic strain …
pandemic threat to humans. Since the deployment of vaccines against a pandemic strain …