Addiction is a chronically relapsing neuropsychiatric disease that occurs in some, but not all,
individuals who use substances of abuse. Relatively little is known about the mechanisms …

Addiction is an international public health problem. It is a polygenic disorder best
understood by accounting for the interplay between genetic and environmental factors. A …

Drug addiction involves long-term behavioral abnormalities that arise in response to
repeated exposure to drugs of abuse in vulnerable individuals. It is a multifactorial syndrome …

Addictions are public health menaces. However, despite advances in addiction research,
the cellular or molecular mechanisms that cause transition from recreational use to addiction …

Addictions are prevalent psychiatric disorders that confer remarkable personal and social
burden. Despite substantial evidence for their moderate, yet robust, heritability (approx …

This chapter will summarize genetics findings derived from various strategies and highlight
important neural markers (or correlates) in some specific and extensively studied genes …

Drug addiction is a common brain disorder that is extremely costly to the individual and to
society. Genetics contributes significantly to vulnerability to this disorder, but identification of …

Addiction to psychoactive substances is a debilitating condition underpinned by the interplay
of genetic and environmental factors. At present, a key challenge for research is to delineate …

Genetic factors are implicated in the heritability of drug abuse. However, even with advances
in current technology no specific genes have been identified that are critical for the …

Addictions are serious and common psychiatric disorders, and are among the leading
contributors to preventable death. This selective review outlines and highlights the need for …