Cryptococcus-macrophage interaction is crucial in the development of cryptococcocal
diseases. C. neoformans and C. gattii are major pathogenic species that occupy different …

Cryptococcal infections are primarily caused by two related fungal species: Cryptococcus
neoformans and Cryptococcus gattii. It is well known that C. neoformans generally affects …

Cryptococcus neoformans is a significant fungal pathogen of immunocompromised patients.
Many questions remain regarding the function of macrophages in normal clearance of …

Cryptococcus neoformans is an opportunistic fungal pathogen that causes lung
inflammation and meningoencephalitis in immunocompromised people. Previously we …

The vast majority of infection with cryptococcal species occurs with Cryptococcus
neoformans in the severely immunocompromised. A significant exception to this is the …

Background Cryptococcus neoformans (C. neoformans) is a globally distributed fungal
pathogen with the potential to cause serious disease, particularly among immune …

Cryptococcosis is an invasive mycosis caused by Cryptococcus spp. that affects the lungs
and the central nervous system (CNS). Due to the severity of the disease, it may occur …

As an infectious fungus that affects the respiratory tract, Cryptococcus neoformans (C.
neoformans) commonly causes asymptomatic pulmonary infection. C. neoformans may …

Upon Cryptococcus neoformans infection of the host lung, the fungus enters a nutrient poor
environment and must adapt to a variety of host-specific stress conditions (temperature …

Macrophages serve as a first line of defense against infection with the facultative
intracellular pathogen, Cryptococcus neoformans (Cn). However, the ability of these innate …