A passion for P450s (remembrances of the early history of research on cytochrome P450)
RW Estabrook - Drug metabolism and disposition, 2003 - ASPET
Many members of the superfamily of hemeproteins, known as cytochrome P450 (P450 or
CYP), are currently described in the literature (over 2000 at the date of this writing)[see …
CYP), are currently described in the literature (over 2000 at the date of this writing)[see …
[图书][B] Cytochrome P450: structure, mechanism, and biochemistry
PRO De Montellano - 2007 - books.google.com
Cytochrome P450: Structure, Mechanism, and Biochemistry, third edition is a revision of a
review that summarizes the current state of research in the field of drug metabolism. The …
review that summarizes the current state of research in the field of drug metabolism. The …
Cytochrome P450 enzymes in drug metabolism and chemical toxicology: An introduction
LL Furge, FP Guengerich - Biochemistry and Molecular Biology …, 2006 - Wiley Online Library
Abstract Cytochrome P450 (P450) enzymes include a family of related enzymes that are
involved in metabolism of vitamins, steroids, fatty acids, and other chemicals. This review …
involved in metabolism of vitamins, steroids, fatty acids, and other chemicals. This review …
[图书][B] Cytochromes P450: role in the metabolism and toxicity of drugs and other xenobiotics
C Ioannides - 2008 - books.google.com
During half a century, cytochrome P450 in its original uniqueness as an optically" wrong"
cytochrome has attracted many investigators, who have contributed to the unveiling of a …
cytochrome has attracted many investigators, who have contributed to the unveiling of a …
Cytochrome P450: what have we learned and what are the future issues?
F Peter Guengerich - Drug metabolism reviews, 2004 - Taylor & Francis
ABSTRACT The cytochrome P450 (P450) field came out of interest in the metabolism of
drugs, carcinogens, and steroids, which remain major focal points. Over the years we have …
drugs, carcinogens, and steroids, which remain major focal points. Over the years we have …
Recent advances: the cytochrome P450 enzymes
RL Slaughter, DJ Edwards - Annals of Pharmacotherapy, 1995 - journals.sagepub.com
THE TERM CYTOCHROME P450 refers to a group of hemecontaining enzymes located on
the membrane of the endoplasmic reticulum. The name derives from the spectral …
the membrane of the endoplasmic reticulum. The name derives from the spectral …
Properties of cytochrome P450 isoenzymes and their substrates part 2: properties of cytochrome P450 substrates
DA Smith, MJ Ackland, BC Jones - Drug Discovery Today, 1997 - infona.pl
Cytochrome P450 isoenzymes are pivotal in drug clearance. Part 1 of this two-part review,
published in the October issue of Drug Discovery Today, described the active site …
published in the October issue of Drug Discovery Today, described the active site …
Human cytochrome P450 enzymes
FP Guengerich - Cytochrome P450: structure, mechanism, and …, 2005 - Springer
Much of P450 research has always been done with the view of appUcation to humans, even
when done with experimental animals and microorganisms. Research with the human …
when done with experimental animals and microorganisms. Research with the human …
Cytochrome P450
FP Guengerich - Enzyme systems that metabolise drugs and …, 2001 - Wiley Online Library
Summary Cytochrome P450 (P450) enzymes are of particular interest because of their
diversity of catalysis of reactions with xenobiotic substrates. The P450s are distributed …
diversity of catalysis of reactions with xenobiotic substrates. The P450s are distributed …
Human cytochrome P450 enzymes
FP Guengerich - Cytochrome P450: structure, mechanism, and …, 2015 - Springer
Abstract The cytochrome P450 (P450) enzymes first attracted interest because of their
relevance to the metabolism of drugs, steroids, and carcinogens. Collectively, the 57 human …
relevance to the metabolism of drugs, steroids, and carcinogens. Collectively, the 57 human …