The purpose of this study was to conduct an overview of systematic reviews (SRs) to
appraise the published evidence related to pharmacological interventions after traumatic …

Introduction Providing current, reliable and evidence based information for clinicians and
researchers in a synthesised and summarised way can be challenging particularly in the …

Traumatic brain injury (TBI) is a major health and socioeconomic problem worldwide with a
high rate of death and long-term disability. Previous studies have summarized evidence …

In this article, we review past and current experience in clinical trials of traumatic brain
injuries (TBIs), we discuss limitations and challenges, and we summarize current directions …

Objective: To evaluate all the possible therapeutic measures concerning the acute
management of traumatic brain injury (TBI) mentioned in Cochrane Systematic Reviews …

Objective To appraise the currency, completeness and quality of evidence from systematic
reviews (SRs) of acute management of moderate to severe traumatic brain injury (TBI) …

Importance Mild traumatic brain injury (TBI) is experienced by 55.9 million people globally
each year. The symptoms of mild TBI are diverse and sometimes long-lasting, requiring …

BACKGROUND: Given the complexity of post-TBI medical, surgical, and rehabilitative care,
research is critical to optimize interventions across the continuum of care and improve …

Traumatic brain injury (TBI) is one of the leading causes of morbidity, disability and mortality
across all age groups globally. Currently, only palliative treatments exist, but these are …

Introduction Traumatic brain injury (TBI) is a major cause of death and disability worldwide.
The deleterious effects of secondary brain injury may be attenuated by early …