Progressive advances in the understanding of retinoblastoma pathogenesis continue to lead
treatment strategies. Improvements in the diagnosis and management of retinoblastoma are …

With an average incidence of 1 in every 18,000 live births, retinoblastoma is a rare type of
intraocular tumour found to affect patients during their early childhood. It is curable if …

Retinoblastoma, the primary ocular malignancy in pediatric patients, poses a substantial
threat to mortality without prompt and effective management. The prognosis for survival and …

Retinoblastoma can present in 1 or both eyes and is the most common intraocular
malignancy in childhood. It is typically initiated by biallelic mutation of the RB1 tumor …

Retinoblastoma is the commonest primary ocular malignancy of childhood. There are two
forms—heritable and non heritable. Heritable retinoblastoma is a cancer susceptibility …

Retinoblastoma is the most common ocular malignancy in children, and is initiated by
mutation of the RB1 gene. The tumor may be unilateral or bilateral and can be inherited …

Purpose To review the progress made in understanding the genetic basis, molecular
pathology, and treatment of retinoblastoma since the previous Jackson lecture on the topic …

Retinoblastoma, the most common intraocular malignancy of childhood arises due to
mutation of the retinoblastoma gene on chromosome 13q14. In the hereditary setting this …

Although rare, retinoblastoma has been at the fore-fortunate; while in the developed world
eye preser-front of cancer research and treatment for the last tion has become a priority …

Retinoblastoma is the most common intraocular cancer of childhood (Shields and Shields
2015; JA and CL 1992; Kivela 2009; Ramasubramanian and Shields 2012a). This …